Midazolam EP Impurity B

Name: Midazolam EP Impurity B
Brand: Vaqora Chemicals
SKU: VQ-031885

About Midazolam EP Impurity B

Listed under CAS 59469-74-8, Midazolam EP Impurity B is a pharmacopeial impurity of Midazolam available from Vaqora Chemicals. Formula C18H13ClFN3, molecular weight 325.8 g/mol. Its systematic (IUPAC) name is 8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine. It is also known as Midazolam 6H- or Midazolam impurity B.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Midazolam, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Midazolam EP Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Midazolam EP Impurity B
Catalogue No.	VQ-031885
CAS Number	59469-74-8
IUPAC name	8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine
Molecular formula	C₁₈H₁₃ClFN₃
Molecular weight	325.8 g/mol
Exact mass	325.0782
Grade	Reference Standard
HSN code	38229090
InChIKey	YXYAKNHSGBDEME-UHFFFAOYSA-N
SMILES	CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(N=C2)C4=CC=CC=C4F
PubChem CID	11045613

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	0 / 3
TPSA	30.2 Å²
Synonyms	Midazolam 6H-, 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo(1,5-a)(1,4)benzodiazepine, 6H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, (6RS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-6H-benzo[f]imidazo[1,5-a][1,4]diazepine, (6RS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine, Midazolam impurity B

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midazolam EP Impurity B?

The CAS Registry Number of Midazolam EP Impurity B is 59469-74-8. It is also known as Midazolam 6H-, 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo(1,5-a)(1,4)benzodiazepine, 6H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-.

What is the molecular formula and molecular weight of Midazolam EP Impurity B?

Midazolam EP Impurity B has the molecular formula C18H13ClFN3 and a molecular weight of 325.8 g/mol. Its IUPAC name is 8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine.

What is Midazolam EP Impurity B used for?

Midazolam EP Impurity B is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midazolam EP Impurity B can I order?

We supply Midazolam EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midazolam EP Impurity B?

Yes. Every lot of Midazolam EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midazolam EP Impurity B be shipped internationally?

Yes. We export Midazolam EP Impurity B worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.