Midazolam EP Impurity D

Name: Midazolam EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-031886

About Midazolam EP Impurity D

Midazolam EP Impurity D (CAS 59468-83-6) is a pharmacopeial impurity of Midazolam offered by Vaqora Chemicals. With the molecular formula C18H13ClFN3O, it has a molar mass of 341.8 g/mol. The IUPAC name is 8-chloro-6-(2-fluorophenyl)-1-methyl-5-oxido-4H-imidazo[1,5-a][1,4]benzodiazepin-5-ium. Common synonyms include Midazolam - Impurity D and Midazolam Oxide Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Midazolam impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Midazolam EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Midazolam

View every impurity, metabolite and intermediate we list for Midazolam.

Midazolam impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Midazolam EP Impurity D
Catalogue No.	VQ-031886
CAS Number	59468-83-6
IUPAC name	8-chloro-6-(2-fluorophenyl)-1-methyl-5-oxido-4H-imidazo[1,5-a][1,4]benzodiazepin-5-ium
Molecular formula	C₁₈H₁₃ClFN₃O
Molecular weight	341.8 g/mol
Exact mass	341.0731
Grade	Reference Standard
HSN code	38229090
InChIKey	FIDBLKWFRFIVLJ-UHFFFAOYSA-N
SMILES	CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=[N+](C2)[O-])C4=CC=CC=C4F
PubChem CID	15563268

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	0 / 3
TPSA	46.6 Å²
Synonyms	Midazolam - Impurity D, Midazolam Oxide Impurity, Midazolam 5-Oxide, Midazolam oxide, 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide, 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, 5-oxide, 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine 5-oxide, (Midazolam 5-Oxide), 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine 5-oxide, 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-5-oxide, 8-Chloro-6-(2-fluorophenyl)-1-methyl-5-oxo-4H-5lambda~5~-imidazo[1,5-a][1,4]benzodiazepine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Midazolam EP Impurity D?

The CAS Registry Number of Midazolam EP Impurity D is 59468-83-6. It is also known as Midazolam - Impurity D, Midazolam Oxide Impurity, Midazolam 5-Oxide.

What is the molecular formula and molecular weight of Midazolam EP Impurity D?

Midazolam EP Impurity D has the molecular formula C18H13ClFN3O and a molecular weight of 341.8 g/mol. Its IUPAC name is 8-chloro-6-(2-fluorophenyl)-1-methyl-5-oxido-4H-imidazo[1,5-a][1,4]benzodiazepin-5-ium.

What is Midazolam EP Impurity D used for?

Midazolam EP Impurity D is supplied as a characterised reference material related to Midazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Midazolam EP Impurity D can I order?

We supply Midazolam EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Midazolam EP Impurity D?

Yes. Every lot of Midazolam EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Midazolam EP Impurity D be shipped internationally?

Yes. We export Midazolam EP Impurity D worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.