Naproxen EP Impurity D

Name: Naproxen EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-023211

About Naproxen EP Impurity D

Naproxen EP Impurity D (CAS 116883-62-6) is a pharmacopeial impurity of Naproxen offered by Vaqora Chemicals. With the molecular formula C14H13IO3, it has a molar mass of 356.15 g/mol. Systematically, it is named (2S)-2-(5-iodo-6-methoxynaphthalen-2-yl)propanoic acid. Common synonyms include Naproxen - Impurity D and 5-Iodonaproxen, (S)-.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Naproxen to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naproxen

View every impurity, metabolite and intermediate we list for Naproxen.

Naproxen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naproxen EP Impurity D
Catalogue No.	VQ-023211
CAS Number	116883-62-6
IUPAC name	(2S)-2-(5-iodo-6-methoxynaphthalen-2-yl)propanoic acid
Molecular formula	C₁₄H₁₃IO₃
Molecular weight	356.15 g/mol
Exact mass	355.9909
Grade	Reference Standard
HSN code	38229090
InChIKey	MNTGUQDQTXNYMT-QMMMGPOBSA-N
SMILES	C[C@@H](C1=CC2=C(C=C1)C(=C(C=C2)OC)I)C(=O)O
PubChem CID	71771710

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 3
TPSA	46.5 Å²
Synonyms	Naproxen - Impurity D, 5-Iodonaproxen, (S)-, 5-Iodo naproxen, (S)-, 2-Naphthaleneacetic acid, 5-iodo-6-methoxy-alpha-methyl-, (S)-, Naproxen impurity D, Naproxen sodium impurity D, (S)-5-Iodo Naproxen, (S)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic acid, (2S)-2-(5-Iodo-6-methoxynaphthalen-2-yl)propanoic Acid (5-Iodonaproxen), (S)-5-iodonaproxen

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P316, P301 + P317, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naproxen EP Impurity D?

The CAS Registry Number of Naproxen EP Impurity D is 116883-62-6. It is also known as Naproxen - Impurity D, 5-Iodonaproxen, (S)-, 5-Iodo naproxen, (S)-.

What is the molecular formula and molecular weight of Naproxen EP Impurity D?

Naproxen EP Impurity D has the molecular formula C14H13IO3 and a molecular weight of 356.15 g/mol. Its IUPAC name is (2S)-2-(5-iodo-6-methoxynaphthalen-2-yl)propanoic acid.

What is Naproxen EP Impurity D used for?

Naproxen EP Impurity D is supplied as a characterised reference material related to Naproxen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naproxen EP Impurity D can I order?

We supply Naproxen EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naproxen EP Impurity D?

Yes. Every lot of Naproxen EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naproxen EP Impurity D be shipped internationally?

Yes. Naproxen EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.