Naproxen EP Impurity E

Name: Naproxen EP Impurity E
Brand: Vaqora Chemicals
SKU: VQ-023208

About Naproxen EP Impurity E

Listed under CAS 26159-35-3, Naproxen EP Impurity E is a pharmacopeial impurity of Naproxen available from Vaqora Chemicals. With the molecular formula C15H16O3, it has a molar mass of 244.28 g/mol. The IUPAC name is methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate. It is also known as Naproxen Sodium impurity E or Naproxen - Impurity E.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Naproxen, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Naproxen EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Naproxen

View every impurity, metabolite and intermediate we list for Naproxen.

Naproxen impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Naproxen EP Impurity E
Catalogue No.	VQ-023208
CAS Number	26159-35-3
IUPAC name	methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
Molecular formula	C₁₅H₁₆O₃
Molecular weight	244.28 g/mol
Exact mass	244.1099
Grade	Reference Standard
HSN code	38229090
InChIKey	ZFYFBPCRUQZGJE-JTQLQIEISA-N
SMILES	C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OC
PubChem CID	9899603

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	Naproxen Sodium impurity E, Naproxen - Impurity E, Naproxen Methyl Ester, (S)-Naproxen Methyl Ester, (+)-Naproxen Methyl Ester, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, methyl ester, (alphaS)-, Naproxen impurity E, (S)-Methyl 2-(6-methoxynaphthalen-2-yl)propanoate, Methyl (S)-2-(6-Methoxynaphthalen-2-yl)propanoate, (S)-Methyl2-(6-methoxynaphthalen-2-yl)propanoate, Methyl (2S)-2-(6-Methoxynaphthalen-2-yl)propanoate (Naproxen Methyl Ester), Monomethyl derivative of Naproxen

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naproxen EP Impurity E?

The CAS Registry Number of Naproxen EP Impurity E is 26159-35-3. It is also known as Naproxen Sodium impurity E, Naproxen - Impurity E, Naproxen Methyl Ester.

What is the molecular formula and molecular weight of Naproxen EP Impurity E?

Naproxen EP Impurity E has the molecular formula C15H16O3 and a molecular weight of 244.28 g/mol. Its IUPAC name is methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate.

What is Naproxen EP Impurity E used for?

Naproxen EP Impurity E is supplied as a characterised reference material related to Naproxen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naproxen EP Impurity E can I order?

We supply Naproxen EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naproxen EP Impurity E?

Yes. Every lot of Naproxen EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naproxen EP Impurity E be shipped internationally?

Yes. Naproxen EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.