Nebivolol

Name: Nebivolol
Brand: Vaqora Chemicals
SKU: VQ-004099

About Nebivolol

Nebivolol (CAS 152520-56-4) is a cardiovascular API offered by Vaqora Chemicals in IP/BP/USP grade with a typical assay of 98%. The compound has the formula C22H26ClF2NO4, corresponding to a molecular weight of 441.9 g/mol. Common synonyms include rac Nebivolol hydrochloride and (R,S,S,S)-nebivolol hydrochloride.

It is supplied as a WHITE CRYSTALLINE POWDER. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As an active pharmaceutical ingredient within our cardiovascular and antihypertensive APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Our customers for this product work in pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Nebivolol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nebivolol
Catalogue No.	VQ-004099
CAS Number	152520-56-4
IUPAC name	(1S)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol;hydrochloride
Molecular formula	C₂₂H₂₆ClF₂NO₄
Molecular weight	441.9 g/mol
Exact mass	441.1518
Grade	IP/BP/USP
Purity / assay	98%
HSN code	2933
InChIKey	JWEXHQAEWHKGCW-BIISKSHESA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O.Cl
PubChem CID	11626384

Physical properties
Physical form	Powder
Appearance	A WHITE CRYSTALLINE POWDER
H-bond donors / acceptors	4 / 7
TPSA	71 Å²
Synonyms	rac Nebivolol hydrochloride, (R,S,S,S)-nebivolol hydrochloride, Nebivolol (hydrochloride), Bystolic (TN), Nebivolol HCl - Bio-X trade mark, Nebivolol (hydrochloride) (Standard), (R,S,S,S)-nebivolol monohydrochloride, Nebivolol hydrochloride, >=98% (HPLC)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P318, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nebivolol?

The CAS Registry Number of Nebivolol is 152520-56-4. It is also known as rac Nebivolol hydrochloride, (R,S,S,S)-nebivolol hydrochloride, Nebivolol (hydrochloride).

What is the molecular formula and molecular weight of Nebivolol?

Nebivolol has the molecular formula C22H26ClF2NO4 and a molecular weight of 441.9 g/mol.

Which grade and pack sizes of Nebivolol can I order?

We supply Nebivolol in IP/BP/USP (98%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nebivolol?

Yes. Every lot of Nebivolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nebivolol be shipped internationally?

Yes. Nebivolol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.