Nebivolol USP Related Compound D

Name: Nebivolol USP Related Compound D
Brand: Vaqora Chemicals
SKU: VQ-023215

About Nebivolol USP Related Compound D

Listed under CAS 793669-26-8, Nebivolol USP Related Compound D is a pharmacopeial impurity of Nebivolol available from Vaqora Chemicals. With the molecular formula C11H11FO2, it has a molar mass of 194.2 g/mol. Systematically, it is named (2S)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene. It is also known as (S,R)-Nebivolol Impurity C or Nebivolol Related Compound D.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nebivolol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Nebivolol USP Related Compound D is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Nebivolol USP Related Compound D
Catalogue No.	VQ-023215
CAS Number	793669-26-8
IUPAC name	(2S)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene
Molecular formula	C₁₁H₁₁FO₂
Molecular weight	194.2 g/mol
Exact mass	194.0743
Grade	Reference Standard
HSN code	38229090
InChIKey	GVZDIJGBXSDSEP-WDEREUQCSA-N
SMILES	C1CC2=C(C=CC(=C2)F)O[C@@H]1[C@H]3CO3
PubChem CID	51698391

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 3
TPSA	21.8 Å²
Synonyms	Nebivolol Epoxide A, Nebivolol USP Related Compound D, (S,R)-Nebivolol Impurity C, Nebivolol Related Compound D, rel-(2R)-6-Fluoro-3,4-dihydro-2-((2S)-2-oxiranyl)-2H-1-benzopyran, rel-(2R)-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran, (+-)-(R,S)-6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran, (2S, 2'S)-6-Fluoro-2-(2'-oxiranyl)chromane, (2S)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-chromene, (+/-)-(R,S)-6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran, Nebivolol Impurity 10, (2S, 2'R)-6-Fluoro-2-(2'-oxiranyl)chromane, (S)-6-fluoro-2-((R)-oxiran-2-yl)chroman

Safety & hazard information (GHS)

Environmental hazard

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements: P273, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nebivolol USP Related Compound D?

The CAS Registry Number of Nebivolol USP Related Compound D is 793669-26-8. It is also known as Nebivolol Epoxide A, Nebivolol USP Related Compound D, (S,R)-Nebivolol Impurity C, Nebivolol Related Compound D.

What is the molecular formula and molecular weight of Nebivolol USP Related Compound D?

Nebivolol USP Related Compound D has the molecular formula C11H11FO2 and a molecular weight of 194.2 g/mol. Its IUPAC name is (2S)-6-fluoro-2-[(2R)-oxiran-2-yl]-3,4-dihydro-2H-chromene.

What is Nebivolol USP Related Compound D used for?

Nebivolol USP Related Compound D is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nebivolol USP Related Compound D can I order?

We supply Nebivolol USP Related Compound D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nebivolol USP Related Compound D?

Yes. Every lot of Nebivolol USP Related Compound D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nebivolol USP Related Compound D be shipped internationally?

Yes. Nebivolol USP Related Compound D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.