Tacrolimus

Name: Tacrolimus
Brand: Vaqora Chemicals
SKU: VQ-007772

About Tacrolimus

Vaqora Chemicals supplies Tacrolimus, a high-purity reference standard of Tacrolimus registered under CAS number 104987-11-3. Its molecular formula is C44H69NO12 and its molecular weight is 804.0 g/mol. Alternative names: Tacropic and Tsukubaenolide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Tacrolimus standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus
Catalogue No.	VQ-007772
CAS Number	104987-11-3
IUPAC name	(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₄H₆₉NO₁₂
Molecular weight	804 g/mol
Exact mass	803.482
Grade	Reference Standard
HSN code	38229090
InChIKey	QJJXYPPXXYFBGM-LFZNUXCKSA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC
PubChem CID	445643

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 12
TPSA	178 Å²
Synonyms	Tacropic, Tsukubaenolide, Envarsus XR, FK 506, Fujimycin, Protopic, Tacrolimus anhydrous, Anhydrous Tacrolimus, Tacrolimus, anhydrous, Astagraf XL, Tacrolimus (anhydrous), (-)-FK 506

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 104987-11-3

IP/BP/USP

Tacrolimus

CAS: 104987-11-3
Formula: C₄₄H₆₉NO₁₂
MW: 804 g/mol

VQ-004253

Frequently asked questions

What is the CAS number of Tacrolimus?

The CAS Registry Number of Tacrolimus is 104987-11-3. It is also known as Tacropic, Tsukubaenolide, Envarsus XR.

What is the molecular formula and molecular weight of Tacrolimus?

Tacrolimus has the molecular formula C44H69NO12 and a molecular weight of 804 g/mol.

What is Tacrolimus used for?

Tacrolimus is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus can I order?

We supply Tacrolimus in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus?

Yes. Every lot of Tacrolimus is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus be shipped internationally?

Yes. Tacrolimus is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.