Tacrolimus

Name: Tacrolimus
Brand: Vaqora Chemicals
SKU: VQ-004253

About Tacrolimus

Tacrolimus is an active pharmaceutical ingredient in IP/BP/USP grade carrying the CAS registry number 104987-11-3. Its molecular formula is C44H69NO12 and its molecular weight is 804.0 g/mol. It is also known as Fujimycin or Tsukubaenolide.

The product is provided as a powder. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our vitamins, excipients and other APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Our customers for this product work in pharmaceutical manufacturing.

Vaqora Chemicals supplies Tacrolimus in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development
Nutraceutical & excipient use

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus
Catalogue No.	VQ-004253
CAS Number	104987-11-3
IUPAC name	(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₄H₆₉NO₁₂
Molecular weight	804 g/mol
Exact mass	803.482
Grade	IP/BP/USP
HSN code	2933
InChIKey	QJJXYPPXXYFBGM-LFZNUXCKSA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC
PubChem CID	445643

Physical properties
Physical form	Powder
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 12
TPSA	178 Å²
Synonyms	Fujimycin, Tsukubaenolide, Protopic, Tacrolimus anhydrous, FK 506, Anhydrous Tacrolimus, Tacrolimus, anhydrous, Astagraf XL, Envarsus XR, Tacrolimus (anhydrous), (-)-FK 506, Anhydrous, Tacrolimus

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P301 + P316, P318, P319, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 104987-11-3

Reference Standard

Tacrolimus

CAS: 104987-11-3
Formula: C₄₄H₆₉NO₁₂
MW: 804 g/mol

In stock

Frequently asked questions

What is the CAS number of Tacrolimus?

The CAS Registry Number of Tacrolimus is 104987-11-3. It is also known as Fujimycin, Tsukubaenolide, Protopic.

What is the molecular formula and molecular weight of Tacrolimus?

Tacrolimus has the molecular formula C44H69NO12 and a molecular weight of 804 g/mol.

What is Tacrolimus used for?

Tacrolimus is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus can I order?

We supply Tacrolimus in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus?

Yes. Every lot of Tacrolimus is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus be shipped internationally?

Yes. Tacrolimus is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.