Boc-(R)-3-Amino-4-phenylbutyric acid

Name: Boc-(R)-3-Amino-4-phenylbutyric acid
Brand: Vaqora Chemicals
SKU: VQ-032498

About Boc-(R)-3-Amino-4-phenylbutyric acid

Vaqora Chemicals supplies Boc-(R)-3-Amino-4-phenylbutyric acid, an impurity of Sitagliptin registered under CAS number 101555-61-7. Formula C15H21NO4, molecular weight 279.33 g/mol. Systematically, it is named (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid. Alternative names: Boc-D-beta-homophenylalanine and Boc-D-b-homophenylalanine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Boc-(R)-3-Amino-4-phenylbutyric acid
Catalogue No.	VQ-032498
CAS Number	101555-61-7
IUPAC name	(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid
Molecular formula	C₁₅H₂₁NO₄
Molecular weight	279.33 g/mol
Exact mass	279.1471
Grade	Reference Standard
HSN code	38229090
InChIKey	ACKWQHCPHJQANL-GFCCVEGCSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](CC1=CC=CC=C1)CC(=O)O
PubChem CID	7021561

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 4
TPSA	75.6 Å²
Synonyms	Boc-D-beta-homophenylalanine, (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoic acid, (3R)-3-(((tert-butoxy)carbonyl)amino)-4-phenylbutanoic acid, (3R)-3-[[(tert-Butoxy)carbonyl]amino]-4-phenylbutanoic acid, (R)-3-tert-Butoxycarbonylamino-4-phenyl-butyric acid, Benzenebutanoic acid, beta-[[(1,1-dimethylethoxy)carbonyl]amino]-, (betaR)-, (R)-3-((tert-butoxycarbonyl)amino)-4-phenylbutanoic acid, (r)-3-(tert-butoxycarbonylamino)-4-phenylbutanoic acid, (3R)-3-[(tert-butoxycarbonyl)amino]-4-phenylbutanoic acid, Boc-D-b-homophenylalanine, Boc-D-beta-HPhe-OH, (3R)-3-(tert-butoxycarbonylamino)-4-phenyl-butanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Boc-(R)-3-Amino-4-phenylbutyric acid?

The CAS Registry Number of Boc-(R)-3-Amino-4-phenylbutyric acid is 101555-61-7. It is also known as Boc-D-beta-homophenylalanine, (3R)-3-{[(tert-butoxy)carbonyl]amino}-4-phenylbutanoic acid, (3R)-3-(((tert-butoxy)carbonyl)amino)-4-phenylbutanoic acid.

What is the molecular formula and molecular weight of Boc-(R)-3-Amino-4-phenylbutyric acid?

Boc-(R)-3-Amino-4-phenylbutyric acid has the molecular formula C15H21NO4 and a molecular weight of 279.33 g/mol. Its IUPAC name is (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid.

What is Boc-(R)-3-Amino-4-phenylbutyric acid used for?

Boc-(R)-3-Amino-4-phenylbutyric acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Boc-(R)-3-Amino-4-phenylbutyric acid can I order?

We supply Boc-(R)-3-Amino-4-phenylbutyric acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Boc-(R)-3-Amino-4-phenylbutyric acid?

Yes. Every lot of Boc-(R)-3-Amino-4-phenylbutyric acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Boc-(R)-3-Amino-4-phenylbutyric acid be shipped internationally?

Yes. Boc-(R)-3-Amino-4-phenylbutyric acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.