Tacrolimus Diene

Name: Tacrolimus Diene
Brand: Vaqora Chemicals
SKU: VQ-028166

About Tacrolimus Diene

Tacrolimus Diene (CAS 104987-16-8) is an impurity of Tacrolimus offered by Vaqora Chemicals. Its molecular formula is C44H67NO11 and its molecular weight is 786.0 g/mol. It is also known as delta23-FK-506 or 23,24-Anhydro tacrolimus.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Tacrolimus, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Tacrolimus Diene in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus Diene
Catalogue No.	VQ-028166
CAS Number	104987-16-8
IUPAC name	(1R,9S,12S,13R,14E,17R,18E,21S,23S,24R,25S,27R)-1-hydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacosa-14,18-diene-2,3,10,16-tetrone
Molecular formula	C₄₄H₆₇NO₁₁
Molecular weight	786 g/mol
Exact mass	785.4714
Grade	Reference Standard
HSN code	38229090
InChIKey	PLHJNIVKYISEQW-ADGUVUBISA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H](/C=C/C(=O)[C@@H](/C=C(/C1)\C)CC=C)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC
PubChem CID	72941634

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 11
TPSA	158 Å²

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H311Toxic in contact with skin
H331Toxic if inhaled

Precautionary statements: P261, P262, P264, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P316, P321, P330, P361 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tacrolimus Diene?

The CAS Registry Number of Tacrolimus Diene is 104987-16-8. It is also known as delta23-FK-506, 23,24-Anhydro tacrolimus.

What is the molecular formula and molecular weight of Tacrolimus Diene?

Tacrolimus Diene has the molecular formula C44H67NO11 and a molecular weight of 786 g/mol.

What is Tacrolimus Diene used for?

Tacrolimus Diene is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus Diene can I order?

We supply Tacrolimus Diene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus Diene?

Yes. Every lot of Tacrolimus Diene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus Diene be shipped internationally?

Yes. Tacrolimus Diene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.