Ponatinib hydrochloride

Name: Ponatinib hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-041556

About Ponatinib hydrochloride

Ponatinib hydrochloride (CAS 1114544-31-8) is a high-purity reference standard of Ponatinib offered by Vaqora Chemicals. With the molecular formula C29H28ClF3N6O, it has a molar mass of 569.0 g/mol. Common synonyms include Ponatinib HCl and Ponatinib Mono-hydrochloride.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Ponatinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ponatinib hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ponatinib hydrochloride
Catalogue No.	VQ-041556
CAS Number	1114544-31-8
IUPAC name	3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide;hydrochloride
Molecular formula	C₂₉H₂₈ClF₃N₆O
Molecular weight	569 g/mol
Exact mass	568.1965
Grade	Reference Standard
HSN code	38229090
InChIKey	BWTNNZPNKQIADY-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5.Cl
PubChem CID	46908927

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 8
TPSA	65.8 Å²
Synonyms	Ponatinib HCl, Ponatinib Mono-hydrochloride, Ponatinib (HCl salt), AP-24534 hydrochloride, Ponatinib hydrochloride (JAN/USAN), EX-A067-1, Ponatinib Hydrochloridenib hydrochloride

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P301 + P317, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ponatinib hydrochloride?

The CAS Registry Number of Ponatinib hydrochloride is 1114544-31-8. It is also known as Ponatinib HCl, Ponatinib Mono-hydrochloride, Ponatinib (HCl salt).

What is the molecular formula and molecular weight of Ponatinib hydrochloride?

Ponatinib hydrochloride has the molecular formula C29H28ClF3N6O and a molecular weight of 569 g/mol.

What is Ponatinib hydrochloride used for?

Ponatinib hydrochloride is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ponatinib hydrochloride can I order?

We supply Ponatinib hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ponatinib hydrochloride?

Yes. Every lot of Ponatinib hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ponatinib hydrochloride be shipped internationally?

Yes. Ponatinib hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.