Letrozole

Name: Letrozole
Brand: Vaqora Chemicals
SKU: VQ-004218

About Letrozole

Listed under CAS 112809-51-5, Letrozole is an anticancer API available from Vaqora Chemicals (IP/BP/USP grade) with a typical assay of 99%. The compound has the formula C17H11N5, corresponding to a molecular weight of 285.3 g/mol. Its systematic (IUPAC) name is 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile. Alternative names: Letrozol and Letrozole Tablets.

It is supplied as a white to off-white powder. Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our oncology APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

We offer Letrozole in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Polymer & resin production
Pharmaceutical formulation

Industries

Related to Letrozole

View every impurity, metabolite and intermediate we list for Letrozole.

Letrozole impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Letrozole
Catalogue No.	VQ-004218
CAS Number	112809-51-5
IUPAC name	4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
Molecular formula	C₁₇H₁₁N₅
Molecular weight	285.3 g/mol
Exact mass	285.1014
Grade	IP/BP/USP
Purity / assay	99%
HSN code	2933
InChIKey	HPJKCIUCZWXJDR-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
PubChem CID	3902

Physical properties
Physical form	Powder
Appearance	White to off-white powder
LogP (XLogP3)	2.7
H-bond donors / acceptors	0 / 4
TPSA	78.3 Å²
Synonyms	Letrozol, Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-, 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile, 4-((4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl)benzonitrile, 4-((4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl)benzonitrile, Letrozole Tablets, 4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile), 4,4'-(1H-1,2,4triazol-1-ylmethylene)dibenzonitrile, 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile, 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile, 1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Letrozole?

The CAS Registry Number of Letrozole is 112809-51-5. It is also known as Letrozol, Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-, 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile.

What is the molecular formula and molecular weight of Letrozole?

Letrozole has the molecular formula C17H11N5 and a molecular weight of 285.3 g/mol. Its IUPAC name is 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile.

What is Letrozole used for?

Letrozole is supplied as a characterised reference material related to Letrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Letrozole can I order?

We supply Letrozole in IP/BP/USP (99%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Letrozole?

Yes. Every lot of Letrozole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Letrozole be shipped internationally?

Yes. Letrozole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.