Neratinib-d6

Name: Neratinib-d6
Brand: Vaqora Chemicals
SKU: VQ-026871

About Neratinib-d6

Neratinib-d6 (CAS 1259519-18-0) is a stable isotope labelled analogue related to Neratinib offered by Vaqora Chemicals. Formula C30H29ClN6O3, molecular weight 563.1 g/mol. It is also known as TMID-1176.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Neratinib-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Neratinib

View every impurity, metabolite and intermediate we list for Neratinib.

Neratinib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Neratinib-d6
Catalogue No.	VQ-026871
CAS Number	1259519-18-0
IUPAC name	(E)-4-[bis(trideuteriomethyl)amino]-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide
Molecular formula	C₃₀H₂₉ClN₆O₃
Molecular weight	563.1 g/mol
Exact mass	562.2366
Grade	Reference Standard
HSN code	38229090
InChIKey	JWNPDZNEKVCWMY-CJSPGLJTSA-N
SMILES	[2H]C([2H])([2H])N(C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)OCC)C([2H])([2H])[2H]
PubChem CID	49870271

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	2 / 8
TPSA	112 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Neratinib-d6?

The CAS Registry Number of Neratinib-d6 is 1259519-18-0. It is also known as TMID-1176.

What is the molecular formula and molecular weight of Neratinib-d6?

Neratinib-d6 has the molecular formula C30H29ClN6O3 and a molecular weight of 563.1 g/mol. Its IUPAC name is (E)-4-[bis(trideuteriomethyl)amino]-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide.

What is Neratinib-d6 used for?

Neratinib-d6 is supplied as a characterised reference material related to Neratinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Neratinib-d6 can I order?

We supply Neratinib-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Neratinib-d6?

Yes. Every lot of Neratinib-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Neratinib-d6 be shipped internationally?

Yes. We export Neratinib-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.