Ribociclib-d6

Name: Ribociclib-d6
Brand: Vaqora Chemicals
SKU: VQ-033532

About Ribociclib-d6

Listed under CAS 1328934-40-2, Ribociclib-d6 is a stable isotope labelled analogue related to Ribociclib available from Vaqora Chemicals. The compound has the formula C23H30N8O, corresponding to a molecular weight of 440.6 g/mol. Alternative names: LEE 011-d6 and TMID-0003.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Its mass shift relative to the unlabelled analyte makes it a dependable internal standard for LC-MS/MS assays, improving accuracy in bioanalysis, therapeutic drug monitoring and method validation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ribociclib-d6 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Ribociclib

View every impurity, metabolite and intermediate we list for Ribociclib.

Ribociclib impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ribociclib-d6
Catalogue No.	VQ-033532
CAS Number	1328934-40-2
IUPAC name	7-cyclopentyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide
Molecular formula	C₂₃H₃₀N₈O
Molecular weight	440.6 g/mol
Exact mass	440.2919
Grade	Reference Standard
HSN code	38229090
InChIKey	RHXHGRAEPCAFML-WFGJKAKNSA-N
SMILES	[2H]C([2H])([2H])N(C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)C([2H])([2H])[2H]
PubChem CID	53348205

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 7
TPSA	91.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ribociclib-d6?

The CAS Registry Number of Ribociclib-d6 is 1328934-40-2. It is also known as LEE 011-d6, TMID-0003.

What is the molecular formula and molecular weight of Ribociclib-d6?

Ribociclib-d6 has the molecular formula C23H30N8O and a molecular weight of 440.6 g/mol. Its IUPAC name is 7-cyclopentyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]-N,N-bis(trideuteriomethyl)pyrrolo[2,3-d]pyrimidine-6-carboxamide.

What is Ribociclib-d6 used for?

Ribociclib-d6 is supplied as a characterised reference material related to Ribociclib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ribociclib-d6 can I order?

We supply Ribociclib-d6 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ribociclib-d6?

Yes. Every lot of Ribociclib-d6 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ribociclib-d6 be shipped internationally?

Yes. We export Ribociclib-d6 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.