Ponatinib Ester Impurity

About Ponatinib Ester Impurity

Ponatinib Ester Impurity is an impurity of Ponatinib carrying the CAS registry number 1356385-96-0. Its molecular formula is C17H13N3O2 and its molecular weight is 291.3 g/mol. Its systematic (IUPAC) name is methyl 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate. Alternative names: Ponatinib Methylbenzoate Impurity.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Ponatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Ponatinib Ester Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ponatinib

View every impurity, metabolite and intermediate we list for Ponatinib.

Ponatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ponatinib Ester Impurity
Catalogue No.	VQ-023515
CAS Number	1356385-96-0
IUPAC name	methyl 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate
Molecular formula	C₁₇H₁₃N₃O₂
Molecular weight	291.3 g/mol
Exact mass	291.1008
Grade	Reference Standard
HSN code	38229090
InChIKey	WIKRCQCIGCKHMQ-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)OC)C#CC2=CN=C3N2N=CC=C3
PubChem CID	68339961

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 4
TPSA	56.5 Å²
Synonyms	Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate, Ponatinib Methylbenzoate Impurity, Methyl 3-(2-(imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methylbenzoate, Benzoic acid, 3-(2-imidazo(1,2-b)pyridazin-3-ylethynyl)-4-methyl-, methyl ester, Benzoic acid, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-, methyl ester, 4. 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-, methyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ponatinib Ester Impurity?

The CAS Registry Number of Ponatinib Ester Impurity is 1356385-96-0. It is also known as Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate, Ponatinib Methylbenzoate Impurity, Methyl 3-(2-(imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methylbenzoate.

What is the molecular formula and molecular weight of Ponatinib Ester Impurity?

Ponatinib Ester Impurity has the molecular formula C17H13N3O2 and a molecular weight of 291.3 g/mol. Its IUPAC name is methyl 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate.

What is Ponatinib Ester Impurity used for?

Ponatinib Ester Impurity is supplied as a characterised reference material related to Ponatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ponatinib Ester Impurity can I order?

We supply Ponatinib Ester Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ponatinib Ester Impurity?

Yes. Every lot of Ponatinib Ester Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ponatinib Ester Impurity be shipped internationally?

Yes. We export Ponatinib Ester Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.