Eszopiclone

About Eszopiclone

Eszopiclone is a central nervous system API (IP/BP/USP grade) carrying the CAS registry number 138729-47-2. Formula C17H17ClN6O3, molecular weight 388.8 g/mol. Systematically, it is named [(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate. It is also known as (S)-Zopiclone or Esopiclone.

In its supplied form it is a white or almost slightly powder (Results:Complies). Keep the container tightly sealed and store it in a cool, dry area. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As an active pharmaceutical ingredient within our CNS and psychiatric APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. Typical end-use sectors are pharmaceutical manufacturing.

We offer Eszopiclone in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Eszopiclone
Catalogue No.	VQ-004041
CAS Number	138729-47-2
IUPAC name	[(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
Molecular formula	C₁₇H₁₇ClN₆O₃
Molecular weight	388.8 g/mol
Exact mass	388.1051
Grade	IP/BP/USP
HSN code	2933
InChIKey	GBBSUAFBMRNDJC-INIZCTEOSA-N
SMILES	CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
PubChem CID	969472

Physical properties
Physical form	Powder
Appearance	White or almost slightly powder (Results:Complies)
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 7
TPSA	91.8 Å²
Synonyms	(S)-Zopiclone, Esopiclone, (+)-Zopiclone, Eszopiclone civ, SEP-190, Zopiclone s-, Zopiclone s-form, C17H17ClN6O3, (S)-Eszopiclone, Estorra (TN), Lunesta (TN), Eszopiclone (S-Zopiclone)

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P316, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Eszopiclone?

The CAS Registry Number of Eszopiclone is 138729-47-2. It is also known as (S)-Zopiclone, Esopiclone, (+)-Zopiclone.

What is the molecular formula and molecular weight of Eszopiclone?

Eszopiclone has the molecular formula C17H17ClN6O3 and a molecular weight of 388.8 g/mol. Its IUPAC name is [(7S)-6-(5-chloro-2-pyridinyl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate.

Which grade and pack sizes of Eszopiclone can I order?

We supply Eszopiclone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Eszopiclone?

Yes. Every lot of Eszopiclone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Eszopiclone be shipped internationally?

Yes. Eszopiclone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.