Paroxetine Hydrochloride Hemihydrate EP Impur… 1395408-54-4

Name: Paroxetine Hydrochloride Hemihydrate EP Impurity C
Brand: Vaqora Chemicals
SKU: VQ-023470

About Paroxetine Hydrochloride Hemihydrate EP Impurity C

Vaqora Chemicals supplies Paroxetine Hydrochloride Hemihydrate EP Impurity C, a pharmacopeial impurity of Paroxetine registered under CAS number 1395408-54-4. Its molecular formula is C21H25NO4 and its molecular weight is 355.4 g/mol. The IUPAC name is (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-ethoxyphenyl)piperidine. Alternative names: Paroxetine Hemihydrate EP Impurity C and Ethoxyparoxetine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Paroxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Paroxetine

View every impurity, metabolite and intermediate we list for Paroxetine.

Paroxetine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Paroxetine Hydrochloride Hemihydrate EP Impurity C
Catalogue No.	VQ-023470
CAS Number	1395408-54-4
IUPAC name	(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-ethoxyphenyl)piperidine
Molecular formula	C₂₁H₂₅NO₄
Molecular weight	355.4 g/mol
Exact mass	355.1784
Grade	Reference Standard
HSN code	38229090
InChIKey	NRDNQJUHWODZBN-LPHOPBHVSA-N
SMILES	CCOC1=CC=C(C=C1)[C@@H]2CCNC[C@H]2COC3=CC4=C(C=C3)OCO4
PubChem CID	71315278

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 5
TPSA	49 Å²
Synonyms	Paroxetine Hydrochloride Hemihydrate EP Impurity C Hydrochloride, Paroxetine Hemihydrate EP Impurity C, Paroxetine Hydrochloride Hemihydrate - Impurity C, (3S,4R)-3-[(1,3-dioxaindan-5-yloxy)methyl]-4-(4-ethoxyphenyl)piperidine, (3S,4R)-3-((1,3-dioxaindan-5-yloxy)methyl)-4-(4-ethoxyphenyl)piperidine, Ethoxyparoxetine, (3S,4R)-3-(((1,3-Benzodioxol-5-yl)oxy)methyl)-4-(4-ethoxyphenyl)piperidine, (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-ethoxyphenyl)piperidine, Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-ethoxyphenyl)-, (3S,4R)-, Paroxetine Hydrochloride Hemihydrate - Impurity C (Freebase), (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-ethoxyphenyl)piperidine hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H303May be harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Paroxetine Hydrochloride Hemihydrate EP Impurity C?

The CAS Registry Number of Paroxetine Hydrochloride Hemihydrate EP Impurity C is 1395408-54-4. It is also known as Paroxetine Hydrochloride Hemihydrate EP Impurity C Hydrochloride, Paroxetine Hemihydrate EP Impurity C, Paroxetine Hydrochloride Hemihydrate - Impurity C.

What is the molecular formula and molecular weight of Paroxetine Hydrochloride Hemihydrate EP Impurity C?

Paroxetine Hydrochloride Hemihydrate EP Impurity C has the molecular formula C21H25NO4 and a molecular weight of 355.4 g/mol. Its IUPAC name is (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-ethoxyphenyl)piperidine.

What is Paroxetine Hydrochloride Hemihydrate EP Impurity C used for?

Paroxetine Hydrochloride Hemihydrate EP Impurity C is supplied as a characterised reference material related to Paroxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Paroxetine Hydrochloride Hemihydrate EP Impurity C can I order?

We supply Paroxetine Hydrochloride Hemihydrate EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Paroxetine Hydrochloride Hemihydrate EP Impurity C?

Yes. Every lot of Paroxetine Hydrochloride Hemihydrate EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Paroxetine Hydrochloride Hemihydrate EP Impurity C be shipped internationally?

Yes. Paroxetine Hydrochloride Hemihydrate EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.