Osimertinib Chloro Impurity

Name: Osimertinib Chloro Impurity
Brand: Vaqora Chemicals
SKU: VQ-007221

About Osimertinib Chloro Impurity

Listed under CAS 1421373-36-5, Osimertinib Chloro Impurity is a metabolite or degradation product of Osimertinib available from Vaqora Chemicals with a typical assay of 92.25%. With the molecular formula C28H34ClN7O2, it has a molar mass of 536.1 g/mol. Alternative names: Osimertinib Degradant Impurity-3.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Osimertinib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Osimertinib Chloro Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Osimertinib Chloro Impurity
Catalogue No.	VQ-007221
CAS Number	1421373-36-5
IUPAC name	3-chloro-N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide
Molecular formula	C₂₈H₃₄ClN₇O₂
Molecular weight	536.1 g/mol
Exact mass	535.2463
Grade	Reference Standard
Purity / assay	92.25%
HSN code	38229090
InChIKey	CZJSVPNNNGPQQQ-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)CCCl)N(C)CCN(C)C)OC
PubChem CID	86677269

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 7
TPSA	87.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Osimertinib Chloro Impurity?

The CAS Registry Number of Osimertinib Chloro Impurity is 1421373-36-5. It is also known as Osimertinib Degradant Impurity-3.

What is the molecular formula and molecular weight of Osimertinib Chloro Impurity?

Osimertinib Chloro Impurity has the molecular formula C28H34ClN7O2 and a molecular weight of 536.1 g/mol. Its IUPAC name is 3-chloro-N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide.

What is Osimertinib Chloro Impurity used for?

Osimertinib Chloro Impurity is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib Chloro Impurity can I order?

We supply Osimertinib Chloro Impurity in Reference Standard (92.25%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib Chloro Impurity?

Yes. Every lot of Osimertinib Chloro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib Chloro Impurity be shipped internationally?

Yes. We export Osimertinib Chloro Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.