L-Thyronine

Name: L-Thyronine
Brand: Vaqora Chemicals
SKU: VQ-034207

About L-Thyronine

L-Thyronine (CAS 1596-67-4) is a high-purity reference standard of Levothyroxine offered by Vaqora Chemicals. With the molecular formula C15H15NO4, it has a molar mass of 273.28 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-3-[4-(4-hydroxyphenoxy)phenyl]propanoic acid. Alternative names: Thyronine and 4-(4-hydroxyphenoxy)-L-phenylalanine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a reference sample of Levothyroxine, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer L-Thyronine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	L-Thyronine
Catalogue No.	VQ-034207
CAS Number	1596-67-4
IUPAC name	(2S)-2-amino-3-[4-(4-hydroxyphenoxy)phenyl]propanoic acid
Molecular formula	C₁₅H₁₅NO₄
Molecular weight	273.28 g/mol
Exact mass	273.1001
Grade	Reference Standard
HSN code	38229090
InChIKey	KKCIOUWDFWQUBT-AWEZNQCLSA-N
SMILES	C1=CC(=CC=C1C[C@@H](C(=O)O)N)OC2=CC=C(C=C2)O
PubChem CID	5461103

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	3 / 5
TPSA	92.8 Å²
Synonyms	Thyronine, 4-(4-hydroxyphenoxy)-L-phenylalanine, (2S)-2-amino-3-(4-(4-hydroxyphenoxy)phenyl)propanoic acid, O-(4-Hydroxyphenyl)-L-tyrosine, Desiodothyroxine, L-Tyrosine, O-(4-hydroxyphenyl)-, O-(4-Hydroxyphenyl)tyrosine, (S)-2-Amino-3-(4-(4-hydroxyphenoxy)phenyl)propanoic acid, H-4-(4-Hydroxyphenoxy)-Phe-OH, L-Tyrosine,O-(4-hydroxyphenyl)-, b-(p-Hydroxyphenoxy)phenylalanine, beta-(p-Hydroxyphenoxy)phenylalanine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-Thyronine?

The CAS Registry Number of L-Thyronine is 1596-67-4. It is also known as Thyronine, 4-(4-hydroxyphenoxy)-L-phenylalanine, (2S)-2-amino-3-(4-(4-hydroxyphenoxy)phenyl)propanoic acid.

What is the molecular formula and molecular weight of L-Thyronine?

L-Thyronine has the molecular formula C15H15NO4 and a molecular weight of 273.28 g/mol. Its IUPAC name is (2S)-2-amino-3-[4-(4-hydroxyphenoxy)phenyl]propanoic acid.

What is L-Thyronine used for?

L-Thyronine is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-Thyronine can I order?

We supply L-Thyronine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-Thyronine?

Yes. Every lot of L-Thyronine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-Thyronine be shipped internationally?

Yes. We export L-Thyronine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.