Aprepitant EP Impurity A

Name: Aprepitant EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-006245

About Aprepitant EP Impurity A

Vaqora Chemicals supplies Aprepitant EP Impurity A, a pharmacopeial impurity of Aprepitant registered under CAS number 170729-76-7. The compound has the formula C23H22F6N4O3, corresponding to a molecular weight of 516.4 g/mol. Alternative names: Defluoro Aprepitant and Desfluoro Aprepitant.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Aprepitant impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Aprepitant EP Impurity A is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Aprepitant EP Impurity A
Catalogue No.	VQ-006245
CAS Number	170729-76-7
IUPAC name	3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Molecular formula	C₂₃H₂₂F₆N₄O₃
Molecular weight	516.4 g/mol
Exact mass	516.1596
Grade	Reference Standard
HSN code	38229090
InChIKey	YOBMIXIISZAQGF-CAYVGHNUSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=CC=C4
PubChem CID	135547943

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	2 / 11
TPSA	75.2 Å²
Synonyms	Defluoro Aprepitant, Desfluoro Aprepitant, Aprepitant Desfluoro, Aprepitant Impurity 8, Aprepitant USP RC A, Aprepitant EP Impurity ADesfluoro Aprepitant, Aprepitant Impurity 8Aprepitant EP Impurity A, Aprepitant impurity 1/Aprepitant EP Impurity A /Defluoro Aprepitant

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprepitant EP Impurity A?

The CAS Registry Number of Aprepitant EP Impurity A is 170729-76-7. It is also known as Defluoro Aprepitant, Desfluoro Aprepitant, Aprepitant Desfluoro.

What is the molecular formula and molecular weight of Aprepitant EP Impurity A?

Aprepitant EP Impurity A has the molecular formula C23H22F6N4O3 and a molecular weight of 516.4 g/mol. Its IUPAC name is 3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-phenylmorpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one.

What is Aprepitant EP Impurity A used for?

Aprepitant EP Impurity A is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprepitant EP Impurity A can I order?

We supply Aprepitant EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprepitant EP Impurity A?

Yes. Every lot of Aprepitant EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprepitant EP Impurity A be shipped internationally?

Yes. We export Aprepitant EP Impurity A worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.