Osimertinib Impurity G (Pre Final)

About Osimertinib Impurity G (Pre Final)

Osimertinib Impurity G (Pre Final) is an impurity of Osimertinib carrying the CAS registry number 1801616-92-1. Formula C22H24N6O, molecular weight 388.5 g/mol. Its systematic (IUPAC) name is 5-methoxy-1-N,1-N-dimethyl-4-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine. It is also known as AZD-9291 Impurity 9.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Osimertinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Osimertinib Impurity G (Pre Final) is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Osimertinib Impurity G (Pre Final)
Catalogue No.	VQ-005447
CAS Number	1801616-92-1
IUPAC name	5-methoxy-1-N,1-N-dimethyl-4-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine
Molecular formula	C₂₂H₂₄N₆O
Molecular weight	388.5 g/mol
Exact mass	388.2012
Grade	Reference Standard
HSN code	38229090
InChIKey	IKEANNIWFABYFE-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)C)OC
PubChem CID	127255563

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 6
TPSA	81.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Osimertinib Impurity G (Pre Final)?

The CAS Registry Number of Osimertinib Impurity G (Pre Final) is 1801616-92-1. It is also known as N'-Desacryloyl N-Desdimethylaminoethyl-N-methyl Osimertinib, AZD-9291 Impurity 9, N'-DesacryloylN-Desdimethylaminoethyl-N-methylOsimertinib.

What is the molecular formula and molecular weight of Osimertinib Impurity G (Pre Final)?

Osimertinib Impurity G (Pre Final) has the molecular formula C22H24N6O and a molecular weight of 388.5 g/mol. Its IUPAC name is 5-methoxy-1-N,1-N-dimethyl-4-N-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine.

What is Osimertinib Impurity G (Pre Final) used for?

Osimertinib Impurity G (Pre Final) is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib Impurity G (Pre Final) can I order?

We supply Osimertinib Impurity G (Pre Final) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib Impurity G (Pre Final)?

Yes. Every lot of Osimertinib Impurity G (Pre Final) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib Impurity G (Pre Final) be shipped internationally?

Yes. We export Osimertinib Impurity G (Pre Final) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.