Nintedanib N-Methyl Aniline Intermediate (n-1) 1987887-92-2

Name: Nintedanib N-Methyl Aniline Intermediate (n-1)
Brand: Vaqora Chemicals
SKU: VQ-013661

About Nintedanib N-Methyl Aniline Intermediate (n-1)

Nintedanib N-Methyl Aniline Intermediate (n-1) (CAS 1987887-92-2) is a process intermediate or related compound of Nintedanib offered by Vaqora Chemicals. The compound has the formula C24H21N3O3, corresponding to a molecular weight of 399.4 g/mol. Systematically, it is named methyl 2-hydroxy-3-[N-[4-(methylamino)phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Nintedanib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Nintedanib N-Methyl Aniline Intermediate (n-1) in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nintedanib N-Methyl Aniline Intermediate (n-1)
Catalogue No.	VQ-013661
CAS Number	1987887-92-2
IUPAC name	methyl 2-hydroxy-3-[N-[4-(methylamino)phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
Molecular formula	C₂₄H₂₁N₃O₃
Molecular weight	399.4 g/mol
Exact mass	399.1583
Grade	Reference Standard
HSN code	2933
InChIKey	MCTPUTLLKUFKQT-UHFFFAOYSA-N
SMILES	CNC1=CC=C(C=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)OC)O
PubChem CID	138462685

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	3 / 5
TPSA	86.7 Å²
Synonyms	(Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (Z)-3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, (E)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, methyl 2-hydroxy-3-(((4-(methylamino)phenyl)imino)(phenyl)methyl)-1H-indole-6-carboxylate, Methyl3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nintedanib N-Methyl Aniline Intermediate (n-1)?

The CAS Registry Number of Nintedanib N-Methyl Aniline Intermediate (n-1) is 1987887-92-2. It is also known as (Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (Z)-3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate.

What is the molecular formula and molecular weight of Nintedanib N-Methyl Aniline Intermediate (n-1)?

Nintedanib N-Methyl Aniline Intermediate (n-1) has the molecular formula C24H21N3O3 and a molecular weight of 399.4 g/mol. Its IUPAC name is methyl 2-hydroxy-3-[N-[4-(methylamino)phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate.

What is Nintedanib N-Methyl Aniline Intermediate (n-1) used for?

Nintedanib N-Methyl Aniline Intermediate (n-1) is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nintedanib N-Methyl Aniline Intermediate (n-1) can I order?

We supply Nintedanib N-Methyl Aniline Intermediate (n-1) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nintedanib N-Methyl Aniline Intermediate (n-1)?

Yes. Every lot of Nintedanib N-Methyl Aniline Intermediate (n-1) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nintedanib N-Methyl Aniline Intermediate (n-1) be shipped internationally?

Yes. We export Nintedanib N-Methyl Aniline Intermediate (n-1) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.