(E)-Methyl-4-(dimethylamino)but-2-enoate

Name: (E)-Methyl-4-(dimethylamino)but-2-enoate
Brand: Vaqora Chemicals
SKU: VQ-024158

About (E)-Methyl-4-(dimethylamino)but-2-enoate

Listed under CAS 212776-19-7, (E)-Methyl-4-(dimethylamino)but-2-enoate is an impurity of Afatinib available from Vaqora Chemicals. Its molecular formula is C7H13NO2 and its molecular weight is 143.18 g/mol. Its systematic (IUPAC) name is methyl (E)-4-(dimethylamino)but-2-enoate. Alternative names: Methyl (2E)-4-(dimethylamino)but-2-enoate and Methyl (2E)-4-(dimethylamino)-2-butenoate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Afatinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (E)-Methyl-4-(dimethylamino)but-2-enoate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Afatinib

View every impurity, metabolite and intermediate we list for Afatinib.

Afatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-Methyl-4-(dimethylamino)but-2-enoate
Catalogue No.	VQ-024158
CAS Number	212776-19-7
IUPAC name	methyl (E)-4-(dimethylamino)but-2-enoate
Molecular formula	C₇H₁₃NO₂
Molecular weight	143.18 g/mol
Exact mass	143.0946
Grade	Reference Standard
HSN code	38229090
InChIKey	CIBYNORTVQSQMW-SNAWJCMRSA-N
SMILES	CN(C)C/C=C/C(=O)OC
PubChem CID	15870798

Physical properties
Physical form	Solid
LogP (XLogP3)	0.4
H-bond donors / acceptors	0 / 3
TPSA	29.5 Å²
Synonyms	trans 4-Dimethylaminocrotonic Acid Methyl Ester, (2E)-4-(Dimethylamino)-2-butenoic acid methyl ester, Methyl (2E)-4-(dimethylamino)but-2-enoate, 2-Butenoic acid, 4-(dimethylamino)-, methyl ester, (2E)-, Methyl (2E)-4-(dimethylamino)-2-butenoate, 2-Butenoicacid,4-(dimethylamino)-,methylester(9CI), (E)-4-(Dimethylamino)but-2-enoic Acid Methyl Ester, (E)-4-(Dimethylamino)-2-butenoic Acid Methyl Ester, methyl 4-dimethylaminocrotonate, Methyl (E)-4-(Dimethylamino)-2-butenoate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-Methyl-4-(dimethylamino)but-2-enoate?

The CAS Registry Number of (E)-Methyl-4-(dimethylamino)but-2-enoate is 212776-19-7. It is also known as trans 4-Dimethylaminocrotonic Acid Methyl Ester, (2E)-4-(Dimethylamino)-2-butenoic acid methyl ester, Methyl (2E)-4-(dimethylamino)but-2-enoate.

What is the molecular formula and molecular weight of (E)-Methyl-4-(dimethylamino)but-2-enoate?

(E)-Methyl-4-(dimethylamino)but-2-enoate has the molecular formula C7H13NO2 and a molecular weight of 143.18 g/mol. Its IUPAC name is methyl (E)-4-(dimethylamino)but-2-enoate.

What is (E)-Methyl-4-(dimethylamino)but-2-enoate used for?

(E)-Methyl-4-(dimethylamino)but-2-enoate is supplied as a characterised reference material related to Afatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-Methyl-4-(dimethylamino)but-2-enoate can I order?

We supply (E)-Methyl-4-(dimethylamino)but-2-enoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-Methyl-4-(dimethylamino)but-2-enoate?

Yes. Every lot of (E)-Methyl-4-(dimethylamino)but-2-enoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-Methyl-4-(dimethylamino)but-2-enoate be shipped internationally?

Yes. We export (E)-Methyl-4-(dimethylamino)but-2-enoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.