Regorafenib Impurity V

Name: Regorafenib Impurity V
Brand: Vaqora Chemicals
SKU: VQ-005722

About Regorafenib Impurity V

Regorafenib Impurity V (CAS 2188236-16-8) is an impurity of Regorafenib offered by Vaqora Chemicals. With the molecular formula C21H16F4N4O3, it has a molar mass of 448.4 g/mol. Systematically, it is named 4-[3-fluoro-4-[[3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide. Alternative names: Deschloro regorafenib and Regorafenib Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Regorafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Regorafenib Impurity V in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Regorafenib Impurity V
Catalogue No.	VQ-005722
CAS Number	2188236-16-8
IUPAC name	4-[3-fluoro-4-[[3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
Molecular formula	C₂₁H₁₆F₄N₄O₃
Molecular weight	448.4 g/mol
Exact mass	448.1159
Grade	Reference Standard
HSN code	38229090
InChIKey	QMSKKPBRQAUZAO-UHFFFAOYSA-N
SMILES	CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC=CC(=C3)C(F)(F)F)F
PubChem CID	75306441

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	3 / 8
TPSA	92.4 Å²
Synonyms	4-(3-fluoro-4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, Deschloro regorafenib, Regorafenib Impurity E, Regorafenib impurity 03, CS-M2815, 4-(3-fluoro-4-(3-(3-(trifluoromethyl)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Regorafenib Impurity V?

The CAS Registry Number of Regorafenib Impurity V is 2188236-16-8. It is also known as 4-(3-fluoro-4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, Deschloro regorafenib, Regorafenib Impurity E.

What is the molecular formula and molecular weight of Regorafenib Impurity V?

Regorafenib Impurity V has the molecular formula C21H16F4N4O3 and a molecular weight of 448.4 g/mol. Its IUPAC name is 4-[3-fluoro-4-[[3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide.

What is Regorafenib Impurity V used for?

Regorafenib Impurity V is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Regorafenib Impurity V can I order?

We supply Regorafenib Impurity V in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Regorafenib Impurity V?

Yes. Every lot of Regorafenib Impurity V is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Regorafenib Impurity V be shipped internationally?

Yes. We export Regorafenib Impurity V worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.