O-Desmethyl Osimertinib Impurity

Name: O-Desmethyl Osimertinib Impurity
Brand: Vaqora Chemicals
SKU: VQ-007210

About O-Desmethyl Osimertinib Impurity

O-Desmethyl Osimertinib Impurity is a metabolite or degradation product of Osimertinib carrying the CAS registry number 2226039-64-9. Formula C27H31N7O2, molecular weight 485.6 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Osimertinib, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies O-Desmethyl Osimertinib Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. SDS and detailed specification sheets can be requested with your quotation.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	O-Desmethyl Osimertinib Impurity
Catalogue No.	VQ-007210
CAS Number	2226039-64-9
IUPAC name	N-[2-[2-(dimethylamino)ethyl-methylamino]-4-hydroxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Molecular formula	C₂₇H₃₁N₇O₂
Molecular weight	485.6 g/mol
Exact mass	485.2539
Grade	Reference Standard
HSN code	38229090
InChIKey	JLZMHKQKKBCKON-UHFFFAOYSA-N
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)O
PubChem CID	141512992

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	3 / 7
TPSA	98.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of O-Desmethyl Osimertinib Impurity?

The CAS Registry Number of O-Desmethyl Osimertinib Impurity is 2226039-64-9.

What is the molecular formula and molecular weight of O-Desmethyl Osimertinib Impurity?

O-Desmethyl Osimertinib Impurity has the molecular formula C27H31N7O2 and a molecular weight of 485.6 g/mol. Its IUPAC name is N-[2-[2-(dimethylamino)ethyl-methylamino]-4-hydroxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide.

What is O-Desmethyl Osimertinib Impurity used for?

O-Desmethyl Osimertinib Impurity is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of O-Desmethyl Osimertinib Impurity can I order?

We supply O-Desmethyl Osimertinib Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with O-Desmethyl Osimertinib Impurity?

Yes. Every lot of O-Desmethyl Osimertinib Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can O-Desmethyl Osimertinib Impurity be shipped internationally?

Yes. We export O-Desmethyl Osimertinib Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.