Macitentan Stage-I Hydroxy Impurity

About Macitentan Stage-I Hydroxy Impurity

Macitentan Stage-I Hydroxy Impurity is a metabolite or degradation product of Macitentan carrying the CAS registry number 2365406-85-3. With the molecular formula C13H15BrN4O3S, it has a molar mass of 387.25 g/mol. Its systematic (IUPAC) name is 5-(4-bromophenyl)-4-(propylsulfamoylamino)-1H-pyrimidin-6-one. It is also known as Macitentan 6-Hydroxy Impurity or Hydroxy Macitentan.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Macitentan, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Macitentan Stage-I Hydroxy Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	Macitentan Stage-I Hydroxy Impurity
Catalogue No.	VQ-023022
CAS Number	2365406-85-3
IUPAC name	5-(4-bromophenyl)-4-(propylsulfamoylamino)-1H-pyrimidin-6-one
Molecular formula	C₁₃H₁₅BrN₄O₃S
Molecular weight	387.25 g/mol
Exact mass	386.0048
Grade	Reference Standard
HSN code	38229090
InChIKey	ULDLQFSOWJYBCO-UHFFFAOYSA-N
SMILES	CCCNS(=O)(=O)NC1=C(C(=O)NC=N1)C2=CC=C(C=C2)Br
PubChem CID	137157140

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	3 / 6
TPSA	108 Å²
Synonyms	N-[5-(4-Bromophenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide, Macitentan 6-Hydroxy Impurity, Hydroxy Macitentan, 5-(p-Bromophenyl)-6-(propylaminosulfonylamino)-4-pyrimidinol, N-[5-(4-Bromophenyl)-1,6-dihydro-6-oxo-4-pyrimidinyl]-N'-propylsulfamide, Sulfamide, N-[5-(4-bromophenyl)-1,6-dihydro-6-oxo-4-pyrimidinyl]-N'-propyl-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Macitentan Stage-I Hydroxy Impurity?

The CAS Registry Number of Macitentan Stage-I Hydroxy Impurity is 2365406-85-3. It is also known as N-[5-(4-Bromophenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsulfamide, Macitentan 6-Hydroxy Impurity, Hydroxy Macitentan.

What is the molecular formula and molecular weight of Macitentan Stage-I Hydroxy Impurity?

Macitentan Stage-I Hydroxy Impurity has the molecular formula C13H15BrN4O3S and a molecular weight of 387.25 g/mol. Its IUPAC name is 5-(4-bromophenyl)-4-(propylsulfamoylamino)-1H-pyrimidin-6-one.

What is Macitentan Stage-I Hydroxy Impurity used for?

Macitentan Stage-I Hydroxy Impurity is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Macitentan Stage-I Hydroxy Impurity can I order?

We supply Macitentan Stage-I Hydroxy Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Macitentan Stage-I Hydroxy Impurity?

Yes. Every lot of Macitentan Stage-I Hydroxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Macitentan Stage-I Hydroxy Impurity be shipped internationally?

Yes. We export Macitentan Stage-I Hydroxy Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.