Aprocitentan-d4

Name: Aprocitentan-d4
Brand: Vaqora Chemicals
SKU: VQ-035510

About Aprocitentan-d4

Aprocitentan-d4 (CAS 2748196-51-0) is a stable isotope labelled analogue related to Macitentan offered by Vaqora Chemicals. Formula C16H14Br2N6O4S, molecular weight 550.2 g/mol. Its systematic (IUPAC) name is 5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxy-1,1,2,2-tetradeuterioethoxy]-6-(sulfamoylamino)pyrimidine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Macitentan and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Aprocitentan-d4 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Aprocitentan-d4
Catalogue No.	VQ-035510
CAS Number	2748196-51-0
IUPAC name	5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxy-1,1,2,2-tetradeuterioethoxy]-6-(sulfamoylamino)pyrimidine
Molecular formula	C₁₆H₁₄Br₂N₆O₄S
Molecular weight	550.2 g/mol
Exact mass	549.9395
Grade	Reference Standard
HSN code	38229090
InChIKey	DKULOVKANLVDEA-NZLXMSDQSA-N
SMILES	[2H]C([2H])(C([2H])([2H])OC1=NC=C(C=N1)Br)OC2=NC=NC(=C2C3=CC=C(C=C3)Br)NS(=O)(=O)N
PubChem CID	131708543

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 10
TPSA	151 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aprocitentan-d4?

The CAS Registry Number of Aprocitentan-d4 is 2748196-51-0.

What is the molecular formula and molecular weight of Aprocitentan-d4?

Aprocitentan-d4 has the molecular formula C16H14Br2N6O4S and a molecular weight of 550.2 g/mol. Its IUPAC name is 5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxy-1,1,2,2-tetradeuterioethoxy]-6-(sulfamoylamino)pyrimidine.

What is Aprocitentan-d4 used for?

Aprocitentan-d4 is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aprocitentan-d4 can I order?

We supply Aprocitentan-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aprocitentan-d4?

Yes. Every lot of Aprocitentan-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aprocitentan-d4 be shipped internationally?

Yes. We export Aprocitentan-d4 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.