Doxazosin EP Impurity D

Name: Doxazosin EP Impurity D
Brand: Vaqora Chemicals
SKU: VQ-025388

About Doxazosin EP Impurity D

Vaqora Chemicals supplies Doxazosin EP Impurity D, a pharmacopeial impurity of Doxazosin registered under CAS number 28888-44-0. Formula C10H10N2O4, molecular weight 222.2 g/mol. Its systematic (IUPAC) name is 6,7-dimethoxy-1H-quinazoline-2,4-dione. It is also known as Doxazosin Mesylate - Impurity D or 6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Doxazosin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Doxazosin EP Impurity D
Catalogue No.	VQ-025388
CAS Number	28888-44-0
IUPAC name	6,7-dimethoxy-1H-quinazoline-2,4-dione
Molecular formula	C₁₀H₁₀N₂O₄
Molecular weight	222.2 g/mol
Exact mass	222.0641
Grade	Reference Standard
HSN code	38229090
InChIKey	KWNQIIMVPSMYEM-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)C(=O)NC(=O)N2)OC
PubChem CID	120081

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 4
TPSA	76.7 Å²
Synonyms	Doxazosin Mesylate - Impurity D, 6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione, 6,7-Dimethoxy-2,4(1H,3H)-quinazolinedione, 6,7-Dimethoxyquinazoline-2,4-dione, 2,4-Dihydroxy-6,7-dimethoxyquinazoline, 6,7-Dimethoxy-2,4-quinazolinedione, 6,7-dimethoxyquinazoline-2,4-diol, 2,4(1H,3H)-Quinazolinedione, 6,7-dimethoxy-, 6,7-dimethoxy-1,2,3,4-tetrahydroquinazoline-2,4-dione, 2,5-Dihydroxy-6,7-dimethoxyquinazoline, 6,7-dimethoxy-1,3-dihydroquinazoline-2,4-dione, Quinazolindi one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxazosin EP Impurity D?

The CAS Registry Number of Doxazosin EP Impurity D is 28888-44-0. It is also known as Doxazosin Mesylate - Impurity D, 6,7-Dimethoxyquinazoline-2,4(1H,3H)-dione, 6,7-Dimethoxy-2,4(1H,3H)-quinazolinedione.

What is the molecular formula and molecular weight of Doxazosin EP Impurity D?

Doxazosin EP Impurity D has the molecular formula C10H10N2O4 and a molecular weight of 222.2 g/mol. Its IUPAC name is 6,7-dimethoxy-1H-quinazoline-2,4-dione.

What is Doxazosin EP Impurity D used for?

Doxazosin EP Impurity D is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxazosin EP Impurity D can I order?

We supply Doxazosin EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxazosin EP Impurity D?

Yes. Every lot of Doxazosin EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxazosin EP Impurity D be shipped internationally?

Yes. Doxazosin EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.