Diltiazem EP Impurity F

Name: Diltiazem EP Impurity F
Brand: Vaqora Chemicals
SKU: VQ-006333

About Diltiazem EP Impurity F

Diltiazem EP Impurity F (CAS 42399-40-6) is a pharmacopeial impurity of Diltiazem offered by Vaqora Chemicals. The compound has the formula C20H24N2O3S, corresponding to a molecular weight of 372.5 g/mol. Its systematic (IUPAC) name is (2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one. It is also known as Desacetyl Diltiazem or O-Desacetyl Diltiazem.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Diltiazem impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Diltiazem EP Impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Diltiazem

View every impurity, metabolite and intermediate we list for Diltiazem.

Diltiazem impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Diltiazem EP Impurity F
Catalogue No.	VQ-006333
CAS Number	42399-40-6
IUPAC name	(2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one
Molecular formula	C₂₀H₂₄N₂O₃S
Molecular weight	372.5 g/mol
Exact mass	372.1508
Grade	Reference Standard
HSN code	38229090
InChIKey	NZHUXMZTSSZXSB-MOPGFXCFSA-N
SMILES	CN(C)CCN1C2=CC=CC=C2S[C@H]([C@H](C1=O)O)C3=CC=C(C=C3)OC
PubChem CID	91638

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 5
TPSA	78.3 Å²
Synonyms	Desacetyl Diltiazem, O-Desacetyl Diltiazem, Deacetyl-d-diltiazem, Desacetyl Diltiaze m, Deacet yldiltiazem, Diltiazem-M deacetyl, Diltiazem impurity F CRS, Desacetyldiltiazem 1.0 mg/ml in Acetonitrile

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H320Causes eye irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P264 + P265, P270, P280, P301 + P317, P305 + P351 + P338, P318, P330, P337 + P317, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Diltiazem EP Impurity F?

The CAS Registry Number of Diltiazem EP Impurity F is 42399-40-6. It is also known as Desacetyl Diltiazem, O-Desacetyl Diltiazem, Deacetyl-d-diltiazem.

What is the molecular formula and molecular weight of Diltiazem EP Impurity F?

Diltiazem EP Impurity F has the molecular formula C20H24N2O3S and a molecular weight of 372.5 g/mol. Its IUPAC name is (2S,3S)-5-[2-(dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one.

What is Diltiazem EP Impurity F used for?

Diltiazem EP Impurity F is supplied as a characterised reference material related to Diltiazem. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Diltiazem EP Impurity F can I order?

We supply Diltiazem EP Impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Diltiazem EP Impurity F?

Yes. Every lot of Diltiazem EP Impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Diltiazem EP Impurity F be shipped internationally?

Yes. Diltiazem EP Impurity F is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.