5-Formyl-5,6,7,8-tetrahydropteroic acid

Name: 5-Formyl-5,6,7,8-tetrahydropteroic acid
Brand: Vaqora Chemicals
SKU: VQ-024076

About 5-Formyl-5,6,7,8-tetrahydropteroic acid

Vaqora Chemicals supplies 5-Formyl-5,6,7,8-tetrahydropteroic acid, an impurity of Folinic Acid registered under CAS number 4349-43-3. Its molecular formula is C15H16N6O4 and its molecular weight is 344.33 g/mol. The IUPAC name is 4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid. Alternative names: 5-Formyltetrahydropteroic Acid and 5-formyl-4HPA.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Folinic Acid, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5-Formyl-5,6,7,8-tetrahydropteroic acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Folinic Acid

View every impurity, metabolite and intermediate we list for Folinic Acid.

Folinic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Formyl-5,6,7,8-tetrahydropteroic acid
Catalogue No.	VQ-024076
CAS Number	4349-43-3
IUPAC name	4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid
Molecular formula	C₁₅H₁₆N₆O₄
Molecular weight	344.33 g/mol
Exact mass	344.1233
Grade	Reference Standard
HSN code	38229090
InChIKey	CQQLECJFFZOOBZ-UHFFFAOYSA-N
SMILES	C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)O
PubChem CID	135991838

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.5
H-bond donors / acceptors	5 / 7
TPSA	149 Å²
Synonyms	5-Formyltetrahydropteroic Acid, 5-formyl-4HPA, 4-(((2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoic acid, 4-(((2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoic acid, 4-[[(2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, (6S)-5-Formyl-5,6,7,8-tetrahydropteroic Acid, 4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Formyl-5,6,7,8-tetrahydropteroic acid?

The CAS Registry Number of 5-Formyl-5,6,7,8-tetrahydropteroic acid is 4349-43-3. It is also known as 5-Formyltetrahydropteroic Acid, 5-formyl-4HPA, 4-(((2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoic acid.

What is the molecular formula and molecular weight of 5-Formyl-5,6,7,8-tetrahydropteroic acid?

5-Formyl-5,6,7,8-tetrahydropteroic acid has the molecular formula C15H16N6O4 and a molecular weight of 344.33 g/mol. Its IUPAC name is 4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid.

What is 5-Formyl-5,6,7,8-tetrahydropteroic acid used for?

5-Formyl-5,6,7,8-tetrahydropteroic acid is supplied as a characterised reference material related to Folinic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Formyl-5,6,7,8-tetrahydropteroic acid can I order?

We supply 5-Formyl-5,6,7,8-tetrahydropteroic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Formyl-5,6,7,8-tetrahydropteroic acid?

Yes. Every lot of 5-Formyl-5,6,7,8-tetrahydropteroic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Formyl-5,6,7,8-tetrahydropteroic acid be shipped internationally?

Yes. 5-Formyl-5,6,7,8-tetrahydropteroic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.