N-Despropyl-N-Ethyl Macitentan

Name: N-Despropyl-N-Ethyl Macitentan
Brand: Vaqora Chemicals
SKU: VQ-021268

About N-Despropyl-N-Ethyl Macitentan

Vaqora Chemicals supplies N-Despropyl-N-Ethyl Macitentan, a metabolite or degradation product of Macitentan registered under CAS number 441796-13-0. Its molecular formula is C18H18Br2N6O4S and its molecular weight is 574.2 g/mol. The IUPAC name is 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Macitentan, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-Despropyl-N-Ethyl Macitentan in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Despropyl-N-Ethyl Macitentan
Catalogue No.	VQ-021268
CAS Number	441796-13-0
IUPAC name	5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine
Molecular formula	C₁₈H₁₈Br₂N₆O₄S
Molecular weight	574.2 g/mol
Exact mass	573.9457
Grade	Reference Standard
HSN code	38229090
InChIKey	PIJUSICWAKBTEZ-UHFFFAOYSA-N
SMILES	CCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
PubChem CID	71462322

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	2 / 10
TPSA	137 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Despropyl-N-Ethyl Macitentan?

The CAS Registry Number of N-Despropyl-N-Ethyl Macitentan is 441796-13-0.

What is the molecular formula and molecular weight of N-Despropyl-N-Ethyl Macitentan?

N-Despropyl-N-Ethyl Macitentan has the molecular formula C18H18Br2N6O4S and a molecular weight of 574.2 g/mol. Its IUPAC name is 5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-N-(ethylsulfamoyl)pyrimidin-4-amine.

What is N-Despropyl-N-Ethyl Macitentan used for?

N-Despropyl-N-Ethyl Macitentan is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Despropyl-N-Ethyl Macitentan can I order?

We supply N-Despropyl-N-Ethyl Macitentan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Despropyl-N-Ethyl Macitentan?

Yes. Every lot of N-Despropyl-N-Ethyl Macitentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Despropyl-N-Ethyl Macitentan be shipped internationally?

Yes. We export N-Despropyl-N-Ethyl Macitentan worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.