Clozapine EP Impurity A

Name: Clozapine EP Impurity A
Brand: Vaqora Chemicals
SKU: VQ-022253

About Clozapine EP Impurity A

Clozapine EP Impurity A is a pharmacopeial impurity of Clozapine carrying the CAS registry number 50892-62-1. The compound has the formula C13H9ClN2O, corresponding to a molecular weight of 244.67 g/mol. Its systematic (IUPAC) name is 3-chloro-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one. It is also known as Clozapine - Impurity A or 8-Chloro-11-oxo-5H-dibenzo[b,e][1,4]diazepine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Clozapine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Clozapine EP Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Clozapine

View every impurity, metabolite and intermediate we list for Clozapine.

Clozapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Clozapine EP Impurity A
Catalogue No.	VQ-022253
CAS Number	50892-62-1
IUPAC name	3-chloro-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
Molecular formula	C₁₃H₉ClN₂O
Molecular weight	244.67 g/mol
Exact mass	244.0403
Grade	Reference Standard
HSN code	38229090
InChIKey	YVWNDABPZGGQFE-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)NC3=C(N2)C=CC(=C3)Cl
PubChem CID	3653116

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 2
TPSA	41.1 Å²
Synonyms	Clozapine - Impurity A, 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one, 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one, 8-Chloro-5,10-Dihydro-11h-Dibenzo[b,E][1,4]diazepin-11-One, 8-Chloro-5, 10-dihydro-11H-dibenzo (b, E) (1, 4) diazepin-11-one, 8-Chloro-5,10-dihydro-11H-dibenzo(b,E)(1,4)diazepin-11-one, 11H-Dibenzo(b,E)(1,4)diazepin-11-one, 8-chloro-5,10-dihydro-, 8-Chloro-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepin-11-one, 8-Chloro-11-oxo-5H-dibenzo[b,e][1,4]diazepine, Clozapine Impurity A, 8-Chloro-5,10-dihydrodebenzo[b,e][1,4]diazepin-11-one, 8-chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one

Safety & hazard information (GHS)

Toxic

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H341Suspected of causing genetic defects

Precautionary statements: P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Clozapine EP Impurity A?

The CAS Registry Number of Clozapine EP Impurity A is 50892-62-1. It is also known as Clozapine - Impurity A, 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one, 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one.

What is the molecular formula and molecular weight of Clozapine EP Impurity A?

Clozapine EP Impurity A has the molecular formula C13H9ClN2O and a molecular weight of 244.67 g/mol. Its IUPAC name is 3-chloro-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one.

What is Clozapine EP Impurity A used for?

Clozapine EP Impurity A is supplied as a characterised reference material related to Clozapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Clozapine EP Impurity A can I order?

We supply Clozapine EP Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Clozapine EP Impurity A?

Yes. Every lot of Clozapine EP Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Clozapine EP Impurity A be shipped internationally?

Yes. Clozapine EP Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.