Spironolactone

Name: Spironolactone
Brand: Vaqora Chemicals
SKU: VQ-004109

About Spironolactone

Vaqora Chemicals supplies Spironolactone (IP/BP/USP grade), a cardiovascular API registered under CAS number 52-01-7. With the molecular formula C24H32O4S, it has a molar mass of 416.6 g/mol. It is also known as Aldactone or Verospirone.

It is supplied as a white or yellowish-white powder. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

As an active pharmaceutical ingredient within our cardiovascular and antihypertensive APIs range, it is offered in IP/BP/USP grade for formulation development, generic drug programmes and commercial manufacturing. It is used across pharmaceutical manufacturing.

We offer Spironolactone in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Spironolactone
Catalogue No.	VQ-004109
CAS Number	52-01-7
IUPAC name	S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
Molecular formula	C₂₄H₃₂O₄S
Molecular weight	416.6 g/mol
Exact mass	416.2021
Grade	IP/BP/USP
InChIKey	LXMSZDCAJNLERA-ZHYRCANASA-N
SMILES	CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
PubChem CID	5833

Physical properties
Physical form	Powder
Appearance	White or yellowish-white powder
LogP (XLogP3)	2.9
H-bond donors / acceptors	0 / 5
TPSA	85.7 Å²
Synonyms	Aldactone, Verospirone, Spirolactone, Uractone, spironolattone, Abbolactone, Laractone, Spironolactone ceva, Spiretic, 7-alpha-(acetylthio)-17-alpha-hydroxy-3-oxopregn-4-ene-21-carboxylic acid, gamma-lactone, Novo Spiroton, Spirono Isis

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P319, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Spironolactone?

The CAS Registry Number of Spironolactone is 52-01-7. It is also known as Aldactone, Verospirone, Spirolactone.

What is the molecular formula and molecular weight of Spironolactone?

Spironolactone has the molecular formula C24H32O4S and a molecular weight of 416.6 g/mol. Its IUPAC name is S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate.

Which grade and pack sizes of Spironolactone can I order?

We supply Spironolactone in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Spironolactone?

Yes. Every lot of Spironolactone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Spironolactone be shipped internationally?

Yes. Spironolactone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.