Levothyroxine Sodium

Name: Levothyroxine Sodium
Brand: Vaqora Chemicals
SKU: VQ-026458

About Levothyroxine Sodium

Levothyroxine Sodium (CAS 55-03-8) is a high-purity reference standard of Levothyroxine offered by Vaqora Chemicals. Formula C15H10I4NNaO4, molecular weight 798.85 g/mol. Its systematic (IUPAC) name is sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate. It is also known as Thyroxine Sodium or L-Thyroxine sodium.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Levothyroxine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Levothyroxine

View every impurity, metabolite and intermediate we list for Levothyroxine.

Levothyroxine impurities

Specifications & identifiers

Chemical identifiers
Product name	Levothyroxine Sodium
Catalogue No.	VQ-026458
CAS Number	55-03-8
IUPAC name	sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
Molecular formula	C₁₅H₁₀I₄NNaO₄
Molecular weight	798.85 g/mol
Exact mass	798.6686
Grade	Reference Standard
HSN code	38229090
InChIKey	YDTFRJLNMPSCFM-YDALLXLXSA-M
SMILES	C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)C[C@@H](C(=O)[O-])N.[Na+]
PubChem CID	23666112

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 5
TPSA	95.6 Å²
Synonyms	Thyroxine Sodium, L-Thyroxine sodium, Levoxyl, Thyroxin sodium, Sodium levothyroxine, Sodium thyroxinate, Levo-T, eltroxin, Sodium L-thyroxine, Thyronamin, Levaxin, Levothyroxine sodium anhydrous

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levothyroxine Sodium?

The CAS Registry Number of Levothyroxine Sodium is 55-03-8. It is also known as Thyroxine Sodium, L-Thyroxine sodium, Levoxyl.

What is the molecular formula and molecular weight of Levothyroxine Sodium?

Levothyroxine Sodium has the molecular formula C15H10I4NNaO4 and a molecular weight of 798.85 g/mol. Its IUPAC name is sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate.

What is Levothyroxine Sodium used for?

Levothyroxine Sodium is supplied as a characterised reference material related to Levothyroxine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levothyroxine Sodium can I order?

We supply Levothyroxine Sodium in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levothyroxine Sodium?

Yes. Every lot of Levothyroxine Sodium is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levothyroxine Sodium be shipped internationally?

Yes. Levothyroxine Sodium is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.