Doxazosin EP Impurity C

About Doxazosin EP Impurity C

Doxazosin EP Impurity C is a pharmacopeial impurity of Doxazosin carrying the CAS registry number 617677-53-9. Its molecular formula is C22H22N2O6 and its molecular weight is 410.4 g/mol. The IUPAC name is [4-(2,3-dihydro-1,4-benzodioxine-3-carbonyl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone. It is also known as Doxazosin Mesylate - Impurity C or Doxazosin impurity C.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Doxazosin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Doxazosin EP Impurity C in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Doxazosin EP Impurity C
Catalogue No.	VQ-025389
CAS Number	617677-53-9
IUPAC name	[4-(2,3-dihydro-1,4-benzodioxine-3-carbonyl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Molecular formula	C₂₂H₂₂N₂O₆
Molecular weight	410.4 g/mol
Exact mass	410.1478
Grade	Reference Standard
HSN code	38229090
InChIKey	RYWJYOGVNZEBKW-UHFFFAOYSA-N
SMILES	C1CN(CCN1C(=O)C2COC3=CC=CC=C3O2)C(=O)C4COC5=CC=CC=C5O4
PubChem CID	4478366

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	0 / 6
TPSA	77.5 Å²
Synonyms	Doxazosin Mesylate - Impurity C, Doxazosin impurity C, 1,4-Bis(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine, Piperazine, 1,4-bis((2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl)-, Doxazosin mesilate impurity C, (+/-)-N,N'-Bis(1,4-benzodioxane-2-carbonyl)piperazine, Piperazine-1,4-diylbis((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone), N,N inverted exclamation mark -Bis(1,4-benzodioxane-2-carbonyl)piperazine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxazosin EP Impurity C?

The CAS Registry Number of Doxazosin EP Impurity C is 617677-53-9. It is also known as Doxazosin Mesylate - Impurity C, Doxazosin impurity C, 1,4-Bis(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine.

What is the molecular formula and molecular weight of Doxazosin EP Impurity C?

Doxazosin EP Impurity C has the molecular formula C22H22N2O6 and a molecular weight of 410.4 g/mol. Its IUPAC name is [4-(2,3-dihydro-1,4-benzodioxine-3-carbonyl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone.

What is Doxazosin EP Impurity C used for?

Doxazosin EP Impurity C is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxazosin EP Impurity C can I order?

We supply Doxazosin EP Impurity C in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxazosin EP Impurity C?

Yes. Every lot of Doxazosin EP Impurity C is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxazosin EP Impurity C be shipped internationally?

Yes. Doxazosin EP Impurity C is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.