Tolbutamide

Name: Tolbutamide
Brand: Vaqora Chemicals
SKU: VQ-004153

About Tolbutamide

Vaqora Chemicals supplies Tolbutamide (IP/BP/USP grade), a metabolic / hormonal API registered under CAS number 64-77-7. Formula C12H18N2O3S, molecular weight 270.35 g/mol. The IUPAC name is 1-butyl-3-(4-methylphenyl)sulfonylurea. It is also known as Arkozal or Butamide.

It is supplied as a powder. Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This API belongs to our antidiabetic, hormone and metabolic APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. It is used across pharmaceutical manufacturing.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tolbutamide
Catalogue No.	VQ-004153
CAS Number	64-77-7
IUPAC name	1-butyl-3-(4-methylphenyl)sulfonylurea
Molecular formula	C₁₂H₁₈N₂O₃S
Molecular weight	270.35 g/mol
Exact mass	270.1038
Grade	IP/BP/USP
HSN code	2933
InChIKey	JLRGJRBPOGGCBT-UHFFFAOYSA-N
SMILES	CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C
PubChem CID	5505

Physical properties
Physical form	Powder
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 3
TPSA	83.7 Å²
Synonyms	Arkozal, Butamide, Willbutamide, Artosin, Ipoglicone, 1-Butyl-3-(p-tolylsulfonyl)urea, 1-Butyl-3-tosylurea, Diabetol, Dolipol, Mobenol, Artozin, Tolbusal

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H370Causes damage to organs

Precautionary statements: P203, P260, P261, P264, P270, P272, P280, P301 + P317, P302 + P352, P308 + P316, P318, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tolbutamide?

The CAS Registry Number of Tolbutamide is 64-77-7. It is also known as Arkozal, Butamide, Willbutamide.

What is the molecular formula and molecular weight of Tolbutamide?

Tolbutamide has the molecular formula C12H18N2O3S and a molecular weight of 270.35 g/mol. Its IUPAC name is 1-butyl-3-(4-methylphenyl)sulfonylurea.

Which grade and pack sizes of Tolbutamide can I order?

We supply Tolbutamide in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tolbutamide?

Yes. Every lot of Tolbutamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tolbutamide be shipped internationally?

Yes. Tolbutamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.