5-(4-Bromophenyl)pyrimidine-4,6-diol

About 5-(4-Bromophenyl)pyrimidine-4,6-diol

5-(4-Bromophenyl)pyrimidine-4,6-diol is an impurity of Macitentan carrying the CAS registry number 706811-25-8. With the molecular formula C10H7BrN2O2, it has a molar mass of 267.08 g/mol. Systematically, it is named 5-(4-bromophenyl)-4-hydroxy-1H-pyrimidin-6-one.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Macitentan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 5-(4-Bromophenyl)pyrimidine-4,6-diol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Macitentan

View every impurity, metabolite and intermediate we list for Macitentan.

Macitentan impurities

Specifications & identifiers

Chemical identifiers
Product name	5-(4-Bromophenyl)pyrimidine-4,6-diol
Catalogue No.	VQ-023014
CAS Number	706811-25-8
IUPAC name	5-(4-bromophenyl)-4-hydroxy-1H-pyrimidin-6-one
Molecular formula	C₁₀H₇BrN₂O₂
Molecular weight	267.08 g/mol
Exact mass	265.9691
Grade	Reference Standard
HSN code	38229090
InChIKey	PIUMVXYVNAISNG-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C2=C(N=CNC2=O)O)Br
PubChem CID	54191439

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 3
TPSA	61.7 Å²
Synonyms	5-(4-broMophenyl)-6-hydroxy-4(1H)-PyriMidinone, 5-(4-bromophenyl)-6-hydroxypyrimidin-4(1H)-one, 4(1H)-Pyrimidinone, 5-(4-bromophenyl)-6-hydroxy-, 5-(4-bromophenyl)-6-hydroxypyrimidin-4(3H)-one, 4(1H)-Pyrimidinone, 5-(4-bromophenyl)-6-hydroxy

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-(4-Bromophenyl)pyrimidine-4,6-diol?

The CAS Registry Number of 5-(4-Bromophenyl)pyrimidine-4,6-diol is 706811-25-8. It is also known as 5-(4-broMophenyl)-6-hydroxy-4(1H)-PyriMidinone, 5-(4-bromophenyl)-6-hydroxypyrimidin-4(1H)-one, 4(1H)-Pyrimidinone, 5-(4-bromophenyl)-6-hydroxy-.

What is the molecular formula and molecular weight of 5-(4-Bromophenyl)pyrimidine-4,6-diol?

5-(4-Bromophenyl)pyrimidine-4,6-diol has the molecular formula C10H7BrN2O2 and a molecular weight of 267.08 g/mol. Its IUPAC name is 5-(4-bromophenyl)-4-hydroxy-1H-pyrimidin-6-one.

What is 5-(4-Bromophenyl)pyrimidine-4,6-diol used for?

5-(4-Bromophenyl)pyrimidine-4,6-diol is supplied as a characterised reference material related to Macitentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-(4-Bromophenyl)pyrimidine-4,6-diol can I order?

We supply 5-(4-Bromophenyl)pyrimidine-4,6-diol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-(4-Bromophenyl)pyrimidine-4,6-diol?

Yes. Every lot of 5-(4-Bromophenyl)pyrimidine-4,6-diol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-(4-Bromophenyl)pyrimidine-4,6-diol be shipped internationally?

Yes. We export 5-(4-Bromophenyl)pyrimidine-4,6-diol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.