5,10-Methenyltetrahydrofolic Acid Impurity

About 5,10-Methenyltetrahydrofolic Acid Impurity

5,10-Methenyltetrahydrofolic Acid Impurity is an impurity of Folinic Acid carrying the CAS registry number 7444-29-3. Formula C20H21N7O6, molecular weight 455.4 g/mol. It is also known as Anhydroleucovorin or 5,10-methenyltetrahydrofolic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Folinic Acid impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg and 50 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Folinic Acid

View every impurity, metabolite and intermediate we list for Folinic Acid.

Folinic Acid impurities

Specifications & identifiers

Chemical identifiers
Product name	5,10-Methenyltetrahydrofolic Acid Impurity
Catalogue No.	VQ-004300
CAS Number	7444-29-3
IUPAC name	(2S)-2-[[4-[(6aR)-3-amino-1-oxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-10-ium-8-yl]benzoyl]amino]-5-hydroxy-5-oxopentanoate
Molecular formula	C₂₀H₂₁N₇O₆
Molecular weight	455.4 g/mol
Exact mass	455.1553
Grade	Reference Standard
HSN code	38229090
InChIKey	MEANFMOQMXYMCT-OLZOCXBDSA-N
SMILES	C1[C@@H]2CN(C=[N+]2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)N[C@@H](CCC(=O)O)C(=O)[O-]
PubChem CID	135450599

Physical properties
Physical form	Solid
LogP (XLogP3)	-1
H-bond donors / acceptors	5 / 8
TPSA	192 Å²
Synonyms	Anhydroleucovorin, 5,10-methenyltetrahydrofolic acid, methenyl-THF, Anhydroleucovorin A, 5,10-methenyl-THF, CH-THF, methenyl-tetrahydrofolate, Methenyltetrahydrofolic acid, n5-n10-CH-THF, n5-n10-methenyltetrahydrofolate, (6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic Acid, anhydro-leucovorin

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,10-Methenyltetrahydrofolic Acid Impurity?

The CAS Registry Number of 5,10-Methenyltetrahydrofolic Acid Impurity is 7444-29-3. It is also known as Anhydroleucovorin, 5,10-methenyltetrahydrofolic acid, methenyl-THF.

What is the molecular formula and molecular weight of 5,10-Methenyltetrahydrofolic Acid Impurity?

5,10-Methenyltetrahydrofolic Acid Impurity has the molecular formula C20H21N7O6 and a molecular weight of 455.4 g/mol. Its IUPAC name is (2S)-2-[[4-[(6aR)-3-amino-1-oxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-10-ium-8-yl]benzoyl]amino]-5-hydroxy-5-oxopentanoate.

What is 5,10-Methenyltetrahydrofolic Acid Impurity used for?

5,10-Methenyltetrahydrofolic Acid Impurity is supplied as a characterised reference material related to Folinic Acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,10-Methenyltetrahydrofolic Acid Impurity can I order?

We supply 5,10-Methenyltetrahydrofolic Acid Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,10-Methenyltetrahydrofolic Acid Impurity?

Yes. Every lot of 5,10-Methenyltetrahydrofolic Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,10-Methenyltetrahydrofolic Acid Impurity be shipped internationally?

Yes. We export 5,10-Methenyltetrahydrofolic Acid Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.