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VAQORARegorafenib Impurity A
Synonyms: 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide · 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide · Regorafenib AFP-PMA Reference Standard · 2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-
CAS No.757251-39-1
FormulaC13H12FN3O2
Mol. weight261.25
Catalogue No.VQ-005719
PurityReference Standard
HSN38229090
Regorafenib Impurity A (CAS 757251-39-1) – Regorafenib impurity standard. C13H12FN3O2, MW 261.25. Supplied by Vaqora Chemicals with COA, exported worldwide.
Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
Enquire Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing
About Regorafenib Impurity A
Regorafenib Impurity A (CAS 757251-39-1) is an impurity of Regorafenib offered by Vaqora Chemicals. Formula C13H12FN3O2, molecular weight 261.25 g/mol. Its systematic (IUPAC) name is 4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide. It is also known as Regorafenib AFP-PMA Reference Standard or Regorafenib EP Impurity A.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Pharmaceutical QC and development laboratories use this impurity standard of Regorafenib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.
We offer Regorafenib Impurity A in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
Related to Regorafenib
View every impurity, metabolite and intermediate we list for Regorafenib.
Regorafenib impuritiesSpecifications & identifiers
| Product name | Regorafenib Impurity A |
|---|---|
| Catalogue No. | VQ-005719 |
| CAS Number | 757251-39-1 |
| IUPAC name | 4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide |
| Molecular formula | C13H12FN3O2 |
| Molecular weight | 261.25 g/mol |
| Exact mass | 261.0914 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | ZQHJPIPGBODVTG-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)N)F |
| PubChem CID | 46835219 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.4 |
| H-bond donors / acceptors | 2 / 5 |
| TPSA | 77.2 Ų |
| Synonyms | 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide, 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide, Regorafenib AFP-PMA Reference Standard, 2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-, Regorafenib EP Impurity A, 4-(4-amino-3-fluorophenoxy)-N-methyl-2-Pyridinecarboxamide, 4-(4-amino-3-fluoro-phenoxy)-pyridine-2-carboxylic acid methylamide, 4-(4Amino-3-fluoro-phenoxy)-pyridine-2-carboxylic acid methylamide, 4-(4-Amino-3-fluo, Regorafenib impurity A CRS, 2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl-, 4-(4-amino-3-fluoro-phenoxy)-N-methyl-pyridine-2-carboxamide |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H302Harmful if swallowedH315Causes skin irritationH319Causes serious eye irritationH411Toxic to aquatic life with long lasting effects
Precautionary statements: P264, P264 + P265, P270, P273, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Regorafenib Impurity A?
The CAS Registry Number of Regorafenib Impurity A is 757251-39-1. It is also known as 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide, 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide, Regorafenib AFP-PMA Reference Standard.
What is the molecular formula and molecular weight of Regorafenib Impurity A?
Regorafenib Impurity A has the molecular formula C13H12FN3O2 and a molecular weight of 261.25 g/mol. Its IUPAC name is 4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide.
What is Regorafenib Impurity A used for?
Regorafenib Impurity A is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Regorafenib Impurity A can I order?
We supply Regorafenib Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Regorafenib Impurity A?
Yes. Every lot of Regorafenib Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Regorafenib Impurity A be shipped internationally?
Yes. Regorafenib Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Regorafenib Impurity A
We reply within one business day with price, pack options, lead time and documentation.
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