Cyclosporin H

Name: Cyclosporin H
Brand: Vaqora Chemicals
SKU: VQ-025121

About Cyclosporin H

Vaqora Chemicals supplies Cyclosporin H, an impurity of Cyclosporine registered under CAS number 83602-39-5. Its molecular formula is C62H111N11O12 and its molecular weight is 1202.6 g/mol. Common synonyms include Cyclosporine H and Csh cyclosporin.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Cyclosporine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cyclosporin H is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cyclosporine

View every impurity, metabolite and intermediate we list for Cyclosporine.

Cyclosporine impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclosporin H
Catalogue No.	VQ-025121
CAS Number	83602-39-5
IUPAC name	(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular formula	C₆₂H₁₁₁N₁₁O₁₂
Molecular weight	1202.6 g/mol
Exact mass	1201.8414
Grade	Reference Standard
HSN code	38229090
InChIKey	PMATZTZNYRCHOR-JLPRAAIDSA-N
SMILES	CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
PubChem CID	6476564

Physical properties
Physical form	Solid
LogP (XLogP3)	7.5
H-bond donors / acceptors	5 / 12
TPSA	279 Å²
Synonyms	Cyclosporine H, Csh cyclosporin, Cyclosporin A, 5-(N-methyl-D-valine)-, 5-(N-Methyl-D-valine)cyclosporine A, [D-MeVal]11-CsA, EX-A2225

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclosporin H?

The CAS Registry Number of Cyclosporin H is 83602-39-5. It is also known as Cyclosporine H, Csh cyclosporin, Cyclosporin A, 5-(N-methyl-D-valine)-.

What is the molecular formula and molecular weight of Cyclosporin H?

Cyclosporin H has the molecular formula C62H111N11O12 and a molecular weight of 1202.6 g/mol.

What is Cyclosporin H used for?

Cyclosporin H is supplied as a characterised reference material related to Cyclosporine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclosporin H can I order?

We supply Cyclosporin H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclosporin H?

Yes. Every lot of Cyclosporin H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclosporin H be shipped internationally?

Yes. Cyclosporin H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.