(2,4-Diaminopteridin-7-yl)methanol

About (2,4-Diaminopteridin-7-yl)methanol

(2,4-Diaminopteridin-7-yl)methanol is an impurity of Methotrexate carrying the CAS registry number 881-33-4. Formula C7H8N6O, molecular weight 192.18 g/mol. Alternative names: 2,4-Diamino-7-Pteridinemethanol and 7-Pteridinemethanol, 2,4-diamino-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Methotrexate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	(2,4-Diaminopteridin-7-yl)methanol
Catalogue No.	VQ-026637
CAS Number	881-33-4
IUPAC name	(2,4-diaminopteridin-7-yl)methanol
Molecular formula	C₇H₈N₆O
Molecular weight	192.18 g/mol
Exact mass	192.076
Grade	Reference Standard
HSN code	38229090
InChIKey	YKUFJEGZKCTYEE-UHFFFAOYSA-N
SMILES	C1=C(N=C2C(=N1)C(=NC(=N2)N)N)CO
PubChem CID	12795843

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.7
H-bond donors / acceptors	3 / 7
TPSA	124 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2,4-Diaminopteridin-7-yl)methanol?

The CAS Registry Number of (2,4-Diaminopteridin-7-yl)methanol is 881-33-4. It is also known as 2,4-Diamino-7-Pteridinemethanol, 7-Pteridinemethanol, 2,4-diamino-.

What is the molecular formula and molecular weight of (2,4-Diaminopteridin-7-yl)methanol?

(2,4-Diaminopteridin-7-yl)methanol has the molecular formula C7H8N6O and a molecular weight of 192.18 g/mol. Its IUPAC name is (2,4-diaminopteridin-7-yl)methanol.

What is (2,4-Diaminopteridin-7-yl)methanol used for?

(2,4-Diaminopteridin-7-yl)methanol is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2,4-Diaminopteridin-7-yl)methanol can I order?

We supply (2,4-Diaminopteridin-7-yl)methanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2,4-Diaminopteridin-7-yl)methanol?

Yes. Every lot of (2,4-Diaminopteridin-7-yl)methanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2,4-Diaminopteridin-7-yl)methanol be shipped internationally?

Yes. We export (2,4-Diaminopteridin-7-yl)methanol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.