(R)-Bortezomib Hydroperoxy Impurity

Name: (R)-Bortezomib Hydroperoxy Impurity
Brand: Vaqora Chemicals
SKU: VQ-020974

About (R)-Bortezomib Hydroperoxy Impurity

Listed under CAS 886979-78-8, (R)-Bortezomib Hydroperoxy Impurity is an impurity of Bortezomib available from Vaqora Chemicals. With the molecular formula C19H24N4O4, it has a molar mass of 372.4 g/mol. Systematically, it is named N-[(2S)-1-[[(1R)-1-hydroperoxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide. Common synonyms include (R)-Hydroperoxy Des(boric Acid) Bortezomib and Bortezomib USP Impurity L.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Bortezomib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-Bortezomib Hydroperoxy Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bortezomib

View every impurity, metabolite and intermediate we list for Bortezomib.

Bortezomib impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Bortezomib Hydroperoxy Impurity
Catalogue No.	VQ-020974
CAS Number	886979-78-8
IUPAC name	N-[(2S)-1-[[(1R)-1-hydroperoxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Molecular formula	C₁₉H₂₄N₄O₄
Molecular weight	372.4 g/mol
Exact mass	372.1798
Grade	Reference Standard
HSN code	38229090
InChIKey	ATPZUYZYORUVIK-DOTOQJQBSA-N
SMILES	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)OO
PubChem CID	91827873

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 6
TPSA	113 Å²
Synonyms	(R)-Hydroperoxy Des(boric Acid) Bortezomib, Bortezomib USP Impurity L, Bortezomib R-Hydroperoxide, tert-butyl 4-((5-phenyl-1,2-oxazol-3-yl)carbamoyl)piperazine-1-carboxylate, Tert-butyl 4-[(5-phenyl-1,2-oxazol-3-yl)carbamoyl]piperazine-1-carboxylate, Bortezomib Impurity M, (S,R)-Hydroperoxy Des(boric Acid) Bortezomib, Bortezomib Impurity 12, Hydroperoxy Des(boric Acid) Bortezomib, (S,R)-, (2S)-N-[(1R)-1-hydroperoxy-3-methylbutyl]-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation

Precautionary statements: P264, P280, P302 + P352, P321, P332 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Bortezomib Hydroperoxy Impurity?

The CAS Registry Number of (R)-Bortezomib Hydroperoxy Impurity is 886979-78-8. It is also known as (R)-Hydroperoxy Des(boric Acid) Bortezomib, Bortezomib USP Impurity L, Bortezomib R-Hydroperoxide.

What is the molecular formula and molecular weight of (R)-Bortezomib Hydroperoxy Impurity?

(R)-Bortezomib Hydroperoxy Impurity has the molecular formula C19H24N4O4 and a molecular weight of 372.4 g/mol. Its IUPAC name is N-[(2S)-1-[[(1R)-1-hydroperoxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide.

What is (R)-Bortezomib Hydroperoxy Impurity used for?

(R)-Bortezomib Hydroperoxy Impurity is supplied as a characterised reference material related to Bortezomib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Bortezomib Hydroperoxy Impurity can I order?

We supply (R)-Bortezomib Hydroperoxy Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Bortezomib Hydroperoxy Impurity?

Yes. Every lot of (R)-Bortezomib Hydroperoxy Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Bortezomib Hydroperoxy Impurity be shipped internationally?

Yes. (R)-Bortezomib Hydroperoxy Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.