2,4-Diamino-6-(hydroxymethyl)pteridine Hydroc… 73978-41-3

Name: 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-031822

About 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride

Listed under CAS 73978-41-3, 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is a metabolite or degradation product of Methotrexate available from Vaqora Chemicals. The compound has the formula C7H9ClN6O, corresponding to a molecular weight of 228.64 g/mol. Common synonyms include 2,4-Diamino-6-(hydroxymethyl)pteridine HCl.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Methotrexate, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
Catalogue No.	VQ-031822
CAS Number	73978-41-3
IUPAC name	(2,4-diaminopteridin-6-yl)methanol;hydrochloride
Molecular formula	C₇H₉ClN₆O
Molecular weight	228.64 g/mol
Exact mass	228.0526
Grade	Reference Standard
HSN code	38229090
InChIKey	XZHMPUJCSYVIQL-UHFFFAOYSA-N
SMILES	C1=C(N=C2C(=NC(=NC2=N1)N)N)CO.Cl
PubChem CID	2725059

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 7
TPSA	124 Å²
Synonyms	(2,4-diaminopteridin-6-yl)methanol Hydrochloride, 6-Pteridinemethanol, 2,4-diamino-, hydrochloride, (2,4-Diamino-6-pteridinyl)methanol hydrochloride, (2,4-diaminopteridin-6-yl)methan-1-ol, chloride, 2,4-Diamino-6-(hydroxymethyl)pteridine HCl, 6-Pteridinemethanol, 2,4-diamino-, monohydrochloride, (2,4-Diaminopteridin-6-yl)methanolhydrochloride, (2,4-Diaminopteridin-6-yl)methanolhydrochloridehydrate, 2,4-Diaminopyrimido[4,5-b]pyrazine-6-methanol monohydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride?

The CAS Registry Number of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is 73978-41-3. It is also known as (2,4-diaminopteridin-6-yl)methanol Hydrochloride, 6-Pteridinemethanol, 2,4-diamino-, hydrochloride, (2,4-Diamino-6-pteridinyl)methanol hydrochloride.

What is the molecular formula and molecular weight of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride?

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride has the molecular formula C7H9ClN6O and a molecular weight of 228.64 g/mol.

What is 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride used for?

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride can I order?

We supply 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride?

Yes. Every lot of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride be shipped internationally?

Yes. 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.