Cabozantinib S-Malate

Name: Cabozantinib S-Malate
Brand: Vaqora Chemicals
SKU: VQ-013279

About Cabozantinib S-Malate

Cabozantinib S-Malate is a process intermediate or related compound of Cabozantinib carrying the CAS registry number 1140909-48-3. Formula C32H30FN3O10, molecular weight 635.6 g/mol. It is also known as Cabozantinib malate or cabozantinib (S)-malate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Cabozantinib, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Cabozantinib S-Malate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Cabozantinib

View every impurity, metabolite and intermediate we list for Cabozantinib.

Cabozantinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cabozantinib S-Malate
Catalogue No.	VQ-013279
CAS Number	1140909-48-3
Other CAS	849217-68-1
IUPAC name	1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
Molecular formula	C₃₂H₃₀FN₃O₁₀
Molecular weight	635.6 g/mol
Exact mass	635.1915
Grade	Reference Standard
HSN code	2933
InChIKey	HFCFMRYTXDINDK-WNQIDUERSA-N
SMILES	COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C([C@@H](C(=O)O)O)C(=O)O
PubChem CID	25102846

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 12
TPSA	194 Å²
Synonyms	Cabozantinib malate, cabozantinib (S)-malate, Cabozantinib malate (XL184), Cabozantinib (S-malate), Cabozantinib L-Malate Salt, XL184(Cabozantinib malate), EX-A2819, Cabometyx (TN), Cometriq (TN), Cabozantinib malate (JAN), Cabozantinib s-malate (USAN), cabozantinib L-malate

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cabozantinib S-Malate?

The CAS Registry Number of Cabozantinib S-Malate is 1140909-48-3. It is also known as Cabozantinib malate, cabozantinib (S)-malate, Cabozantinib malate (XL184).

What is the molecular formula and molecular weight of Cabozantinib S-Malate?

Cabozantinib S-Malate has the molecular formula C32H30FN3O10 and a molecular weight of 635.6 g/mol.

What is Cabozantinib S-Malate used for?

Cabozantinib S-Malate is supplied as a characterised reference material related to Cabozantinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cabozantinib S-Malate can I order?

We supply Cabozantinib S-Malate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cabozantinib S-Malate?

Yes. Every lot of Cabozantinib S-Malate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cabozantinib S-Malate be shipped internationally?

Yes. Cabozantinib S-Malate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.