Bosentan

Name: Bosentan
Brand: Vaqora Chemicals
SKU: VQ-004082

About Bosentan

Vaqora Chemicals supplies Bosentan (IP/BP/USP grade), a cardiovascular API registered under CAS number 147536-97-8 at a purity of ≥98.0%. Formula C27H29N5O6S, molecular weight 551.6 g/mol. Its systematic (IUPAC) name is 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide. It is also known as bosentan anhydrous or Anhydrous bosentan.

The material typically appears as a white crystalline powder(Result:Conforms). Keep the container tightly sealed and store it in a cool, dry area. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our cardiovascular and antihypertensive APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Buyers come mainly from pharmaceutical manufacturing.

Vaqora Chemicals supplies Bosentan in 1 kg, 5 kg and 25 kg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Bosentan

View every impurity, metabolite and intermediate we list for Bosentan.

Bosentan impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Bosentan
Catalogue No.	VQ-004082
CAS Number	147536-97-8
IUPAC name	4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Molecular formula	C₂₇H₂₉N₅O₆S
Molecular weight	551.6 g/mol
Exact mass	551.1839
Grade	IP/BP/USP
Purity / assay	≥98.0%
HSN code	2933
InChIKey	GJPICJJJRGTNOD-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
PubChem CID	104865

Physical properties
Physical form	Powder
Appearance	White crystalline powder(Result:Conforms)
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 11
TPSA	154 Å²
Synonyms	bosentan anhydrous, Anhydrous bosentan, Bosentan (INN), Bosentan (Standard), 147536-97-8 (free), starbld0043886, Bosentan (as monohydrate), Bosentan - Bio-X trade mark

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P264, P270, P273, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Bosentan?

The CAS Registry Number of Bosentan is 147536-97-8. It is also known as bosentan anhydrous, Anhydrous bosentan, Bosentan (INN).

What is the molecular formula and molecular weight of Bosentan?

Bosentan has the molecular formula C27H29N5O6S and a molecular weight of 551.6 g/mol. Its IUPAC name is 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide.

What is Bosentan used for?

Bosentan is supplied as a characterised reference material related to Bosentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Bosentan can I order?

We supply Bosentan in IP/BP/USP (≥98.0%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Bosentan?

Yes. Every lot of Bosentan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Bosentan be shipped internationally?

Yes. Bosentan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.