Methotrexate EP Impurity G

Name: Methotrexate EP Impurity G
Brand: Vaqora Chemicals
SKU: VQ-035031

About Methotrexate EP Impurity G

Vaqora Chemicals supplies Methotrexate EP Impurity G, a pharmacopeial impurity of Methotrexate registered under CAS number 2519848-42-9. Its molecular formula is C28H29N9O6 and its molecular weight is 587.6 g/mol. It is also known as Methotrexate EP Impurity G (Free Base) or Methotrexate - Impurity G.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Methotrexate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Methotrexate

View every impurity, metabolite and intermediate we list for Methotrexate.

Methotrexate impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Methotrexate EP Impurity G
Catalogue No.	VQ-035031
CAS Number	2519848-42-9
IUPAC name	(2S)-2-[[4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]-methylamino]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₈H₂₉N₉O₆
Molecular weight	587.6 g/mol
Exact mass	587.2241
Grade	Reference Standard
HSN code	38229090
InChIKey	HTBPLFOCHFUAFG-FQEVSTJZSA-N
SMILES	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N(C)C4=CC=C(C=C4)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	76962637

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	5 / 13
TPSA	231 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methotrexate EP Impurity G?

The CAS Registry Number of Methotrexate EP Impurity G is 2519848-42-9. It is also known as Methotrexate EP Impurity G (Free Base), Methotrexate - Impurity G.

What is the molecular formula and molecular weight of Methotrexate EP Impurity G?

Methotrexate EP Impurity G has the molecular formula C28H29N9O6 and a molecular weight of 587.6 g/mol. Its IUPAC name is (2S)-2-[[4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]-methylamino]benzoyl]amino]pentanedioic acid.

What is Methotrexate EP Impurity G used for?

Methotrexate EP Impurity G is supplied as a characterised reference material related to Methotrexate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methotrexate EP Impurity G can I order?

We supply Methotrexate EP Impurity G in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methotrexate EP Impurity G?

Yes. Every lot of Methotrexate EP Impurity G is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methotrexate EP Impurity G be shipped internationally?

Yes. We export Methotrexate EP Impurity G worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.