Trametinib Cyclopropyl Amide Impurity

Name: Trametinib Cyclopropyl Amide Impurity
Brand: Vaqora Chemicals
SKU: VQ-006058

About Trametinib Cyclopropyl Amide Impurity

Trametinib Cyclopropyl Amide Impurity (CAS 3018911-27-5) is an impurity of Trametinib offered by Vaqora Chemicals with a typical assay of 95%. Its molecular formula is C17H17FIN3O3 and its molecular weight is 457.24 g/mol. The IUPAC name is N-cyclopropyl-2-(2-fluoro-4-iodoanilino)-4-hydroxy-1,5-dimethyl-6-oxopyridine-3-carboxamide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Trametinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Trametinib Cyclopropyl Amide Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trametinib

View every impurity, metabolite and intermediate we list for Trametinib.

Trametinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Trametinib Cyclopropyl Amide Impurity
Catalogue No.	VQ-006058
CAS Number	3018911-27-5
IUPAC name	N-cyclopropyl-2-(2-fluoro-4-iodoanilino)-4-hydroxy-1,5-dimethyl-6-oxopyridine-3-carboxamide
Molecular formula	C₁₇H₁₇FIN₃O₃
Molecular weight	457.24 g/mol
Exact mass	457.0299
Grade	Reference Standard
Purity / assay	95%
HSN code	38229090
InChIKey	FGZABESIXPRNLG-UHFFFAOYSA-N
SMILES	CC1=C(C(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NC3CC3)O
PubChem CID	169436317

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 5
TPSA	81.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trametinib Cyclopropyl Amide Impurity?

The CAS Registry Number of Trametinib Cyclopropyl Amide Impurity is 3018911-27-5.

What is the molecular formula and molecular weight of Trametinib Cyclopropyl Amide Impurity?

Trametinib Cyclopropyl Amide Impurity has the molecular formula C17H17FIN3O3 and a molecular weight of 457.24 g/mol. Its IUPAC name is N-cyclopropyl-2-(2-fluoro-4-iodoanilino)-4-hydroxy-1,5-dimethyl-6-oxopyridine-3-carboxamide.

What is Trametinib Cyclopropyl Amide Impurity used for?

Trametinib Cyclopropyl Amide Impurity is supplied as a characterised reference material related to Trametinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trametinib Cyclopropyl Amide Impurity can I order?

We supply Trametinib Cyclopropyl Amide Impurity in Reference Standard (95%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trametinib Cyclopropyl Amide Impurity?

Yes. Every lot of Trametinib Cyclopropyl Amide Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trametinib Cyclopropyl Amide Impurity be shipped internationally?

Yes. We export Trametinib Cyclopropyl Amide Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.