ent-Aprepitant

Name: ent-Aprepitant
Brand: Vaqora Chemicals
SKU: VQ-024342

About ent-Aprepitant

ent-Aprepitant (CAS 172822-29-6) is an impurity of Aprepitant offered by Vaqora Chemicals. Its molecular formula is C23H21F7N4O3 and its molecular weight is 534.4 g/mol.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Aprepitant impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer ent-Aprepitant in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Aprepitant

View every impurity, metabolite and intermediate we list for Aprepitant.

Aprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	ent-Aprepitant
Catalogue No.	VQ-024342
CAS Number	172822-29-6
IUPAC name	3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Molecular formula	C₂₃H₂₁F₇N₄O₃
Molecular weight	534.4 g/mol
Exact mass	534.1502
Grade	Reference Standard
HSN code	38229090
InChIKey	ATALOFNDEOCMKK-KNMUDHKVSA-N
SMILES	C[C@@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@H]2[C@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F
PubChem CID	135934925

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 12
TPSA	75.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P264, P270, P273, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of ent-Aprepitant?

The CAS Registry Number of ent-Aprepitant is 172822-29-6.

What is the molecular formula and molecular weight of ent-Aprepitant?

ent-Aprepitant has the molecular formula C23H21F7N4O3 and a molecular weight of 534.4 g/mol. Its IUPAC name is 3-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one.

What is ent-Aprepitant used for?

ent-Aprepitant is supplied as a characterised reference material related to Aprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of ent-Aprepitant can I order?

We supply ent-Aprepitant in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with ent-Aprepitant?

Yes. Every lot of ent-Aprepitant is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can ent-Aprepitant be shipped internationally?

Yes. ent-Aprepitant is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.