Irinotecan

Name: Irinotecan
Brand: Vaqora Chemicals
SKU: VQ-004216

About Irinotecan

Irinotecan is an anticancer API in IP/BP/USP grade carrying the CAS registry number 97682-44-5, specified at ≥98% purity. Its molecular formula is C33H38N4O6 and its molecular weight is 586.7 g/mol. Common synonyms include (+)-Irinotecan and Irinophore C.

The material typically appears as a creamish to pale yellow powder. Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This API belongs to our oncology APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. Typical end-use sectors are pharmaceutical manufacturing.

Available in 1 kg, 5 kg and 25 kg packs, Irinotecan is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Polymer & resin production
Pharmaceutical formulation

Industries

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Irinotecan
Catalogue No.	VQ-004216
CAS Number	97682-44-5
IUPAC name	[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate
Molecular formula	C₃₃H₃₈N₄O₆
Molecular weight	586.7 g/mol
Exact mass	586.2791
Grade	IP/BP/USP
Purity / assay	≥98%
HSN code	2933
InChIKey	UWKQSNNFCGGAFS-XIFFEERXSA-N
SMILES	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7
PubChem CID	60838

Physical properties
Physical form	Powder
Appearance	Creamish to pale yellow powder
LogP (XLogP3)	3
H-bond donors / acceptors	1 / 8
TPSA	113 Å²
Synonyms	(+)-Irinotecan, Irinophore C, Irinotecan lactone, Irinotecan mylan, camptothecin-11, (+)-7-ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate, SN-38-11, 7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycamptothecin, Camptothecin 11, Irinotecan Free base, Irinotecan (INN)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Irinotecan?

The CAS Registry Number of Irinotecan is 97682-44-5. It is also known as (+)-Irinotecan, Irinophore C, Irinotecan lactone.

What is the molecular formula and molecular weight of Irinotecan?

Irinotecan has the molecular formula C33H38N4O6 and a molecular weight of 586.7 g/mol.

Which grade and pack sizes of Irinotecan can I order?

We supply Irinotecan in IP/BP/USP (≥98%) grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Irinotecan?

Yes. Every lot of Irinotecan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Irinotecan be shipped internationally?

Yes. Irinotecan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.